摘要
本論文分為兩個部分作為研究主題，第一部份為利用熱脫附系統搭配氣相層析質譜儀分析液晶顯示器製造廠（LCD）廠中揮發性有機物，第二部分則為以衝擊瓶搭配熱脫附系統/氣相層析質譜儀分析水體中之揮發性有機物。茲分述如下：

第一部份:

本研究為利用自動化連續採樣器進行24小時採樣，每小時採一次，採樣後以冷凍濃縮自動熱脫附儀配合氣相層析質譜儀，對作業環境中之10種揮發性有機化合物(VOCs)進行定性及定量分析。

在採樣方法上，利用多重床採樣管，於常溫下採集樣品，多重床採樣管內填充0.2克Carbopack C、0.2克Carbopack B和0.2克Carbosieve SⅢ，以冷凍熱脫附方式進樣，探討儀器之最佳化條件。

在採樣體積為1升，相對濕度80%的條件下，方法偵測極限為0.38ppb∼0.78ppb，平均樣品回收率則介於96.2% ~ 98.2%之間。

將所建立之方法實際應用於液晶顯示器製造廠之現場量測，A廠量測結果以丙二醇單甲基醚醋酸酯之平均濃度288.7ppb為最高，乙酸正丁酯之平均濃度237ppb次之。B廠量測結果中顯示，丙酮在每個製程區皆有被測得，以曝光區中濃度695.7ppb為最高，配向膜形成區之濃度1.5ppbv最低，而丙二醇單甲基醚醋酸酯在光阻塗怖區濃度為最高，為23.1ppbv。

第二部分:

本研究為衝擊瓶搭配熱脫附系統/氣相層析質譜儀，利用氮氣將樣品自水樣中吹除至吸附管中，在樣品水氣去除方面，利用氦氣進行乾吹除的方式進行除水，再將吸附管進行熱脫附而使樣品進入氣相層析質譜儀進行分析。

在樣品採集方面，利用ISCO 6100自動化採樣器進行揮發性有機化合物的採集，所以需針對針對ISCO 6100自動化採樣器進行QA/QC測試(24小時樣品儲存穩定性測試)。

因本研究的衝擊瓶為自製的，需針對其進行樣品吹除的最佳化測試探討，尋求最佳化條件。並將整個系統應用到環境實測上。

選定污水處理廠為採樣地點，針對3個進水口與2個出水口進行探討，主要的揮發性有機物為丙酮、甲基異丁基酮、二甲基硫化物，其中二甲基硫化物主要為臭味來源。經過進水口與出水口之間的濃度關係，計算其處理效率，Acetone處理效率90.9%，2-Butanone處理效率73.4%，MIBK處理效率95.2%。

Abstract
Part One:

This research is probe into developing a method to qualitative and quantitative measurement of 10 volatile organic compound by using 24 hrs autosampler which gathered samples hourly.

To the aspect of smapling method, multi-sorbent which inside filled with 0.2g Carbopack C, 0.2g Carbopack B and 0.2g Carbosieve SⅢ were used to gather sample under the room temperature. The samples were injected to GC/MS by thermal desorption system.

Under the condition of 80% relative humidity and 1 liter sampling volume, the result showed that the MDL was from 0.38 to 0.78ppbv and the relative recovery yield was range from 96.2% to 98.2%.

Appplying this method to LCD manufactory, 11 target compounds were measured successfully. The average concentration of Propylene glycol methyl ether acetate (PGMEA), butyl acetate and acetone were 288.7ppbv, 237.0ppbv and 75.9ppbv in A manufactory. In B manufactory, acetone was measure in every manufactural process section. The concentration of acetone was 695.7 ppbv in the photolithography process. While the concentration of propylene glycol methyl ether acetate (PGMEA) was 23.1 ppbv in photoresist zone.

Part two:

This research is aim to develop a method of qualitative and quantitative measurement of volatile organic compounds in the water by using impinger couple with cryogenic condensation-thermal desorption system. Sample was purged through impinger by nitrogen gas and gathered onto multi-sorent tube. In order to eliminate moisture interference, the multi-sorbent tube was dry-purged by helium gas.

In the aspect of sampling, we used ISCO 6100 auto-sampler to collect the wastewater from the wastewater treatment factory. The result show that the major volatile organic compounds such as acetone, methyl isobutyl ketone, and dimethylsulfide were measured. Form the realtionship of their concentration, we calculate their efficiency of wastewater treatment respectively. The average efficiency of treatment of acetone was 90.9%, 2-butanone was 73.4%, and methyl isobutyl ketone was 95.2%.

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