氣體感測具有檢測快速與過程簡便的優點，有發展應用到診斷疾病的趨勢，進行快速的診斷，或是用於追蹤慢性疾病之病況。尤其肝臟疾病已成為國人不可
忽視的問題，目前肝臟疾病檢測通常是透過血液檢測或影像學的判定，無法做立即性檢測及追蹤，對於高危險群與肝病患者相當不便。因呼氣中的特定氣體能反應人體臟器健康，能夠由呼氣中特定氣體的濃度來協助判斷肝臟的代謝情形，再利用氨氣氣體感測器，可以達到非侵入式的檢測方式，有助於肝臟疾病的早期預警與居家照顧。人體呼氣組成非常複雜，氣體感測用於人體呼氣檢測將面臨選擇性的問題，由揮發性氣體與感測器產生反應的活化能與濃度計算，欲使用氮化銦氣體感測器進行呼氣檢測需克服干擾氣體丙酮的影響。為了實踐攜帶式肝病呼氣感測裝置，需要達到選擇性，而使用矽油作為前處理的系統，並探討矽油黏度與官能基對於去除干擾源和保留主要訊號的影響。氯矽烷聚合會使矽油具不同種官能基以及不同黏度，矽油黏度會貢獻流動中的阻力，影響液相質傳系數，導致前處理過程中的氣液相交接面形成不同的互動模式，黏度較大會降低氣體分子於溶液中能接觸溶劑分子數目，而降低吸附效果。為了提升丙酮吸附效果，要提升丙酮對矽油的溶解率，溶劑化現象是否能夠發生取決於分子間力以及氫鍵的形成，由於丙酮氫鍵受體強，需要選擇氫鍵施體能力強的官能基才能有效吸附丙酮。由此本篇研究結果，使用低黏度之羥基矽油可有
效降低丙酮干擾。

The advantages of gas detection technology is short time detection and process simple. There is a trend to use gas detection to diagnose. For chronic disease, the gas detection diagnosis is promising to achieve long-term and home care. Especially for liver disease, which is top-ten-causes death in Taiwan. The reason is liver hard to be diagnosed which is inconvenient for the patient. Some researches indicate the specific gas in human exhaled breath behave the condition of organ. Therefore, gas detection used on liver diagnosis is promising candidate. The species in human breath is complex which the sensor need to face the selectivity issue. Based on the sensor and gas activation energy research, the main interference for the InN sensor is acetone. In the research, try to use silicone oil as pretreatment to reduce the influence of acetone and investigate the viscosity and functional groups of silicone oil how to relate the absorption efficiency. Silicone oil is formed by polymerization of siloxane. According to the degree of polymerization, the viscosity would be different and contribute the flow resistance to influence the mass transfer coefficient in liquid-gas phase and flow motions. The higher viscosity would lower the molecular number that gas traveled in liquid phase so that the absorption rate would decrease. To enhance the acetone-absorption rate, the solvation need to form easily. Solvation is depend on intermolecular force and hydrogen bonding. Acetone own higher hydrogen bonding accepter ability so that the silicone oil should own hydroxyl group as match. So the low viscosity and hydroxyl silicone oil is most effective to reduce the influence of acetone.

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