細胞與組織工程近年來已是快速發展且被認為是影響未來人類生活極大的新興科技領域。細胞與細胞(尤其是腦神經細胞)之間是如何交互影響與溝通，一直是深深吸引科學界的研究議題。礙於傳統實驗技術的限制，該研究領域始終難以取得決定性的發展。
本研究提出一整合型生醫奈微晶片，將單一細胞定位、短時間藥物抽換測試、毛細管電泳、即時細胞釋出物與電化學訊號偵測等功能使用微機電技術全部整合封裝於單一晶片上，利用微系統準確、精密、可平行運作的特性來克服以往傳統技術難以克服的瓶頸。如微電泳晶片可大幅縮短即時檢測的取樣時間間距，微流道細胞定位技術使單一細胞擷取培養更準確穩定而減少不必要的干擾，微流道藥物抽換使藥物對細胞間反應能更準確的被測量而較無人為誤差影響。
在製作方面，本研究大量使用了微系統與生醫方面技術。晶片主體由玻璃材料燒結而成，內含以蝕刻形成的電泳微流道。晶片上部則有以SU-8厚膜光組構成的單一細胞分離定位流道與藥物抽換試驗流道，並以可讓細胞貼盤生長的膠原蛋白鋪盤處理，最後並整合螢光偵測或是電化學偵測設計於電泳流道末端。此晶片預期將能解決大部分傳統技術難以突破的研究困境。

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