摘要

本論文主要目的是研究具由丙二烯支鏈之α-碘基酮的離子性環化反應。利用本實驗室所發展的方法製備出具有的丙二烯支鏈之α-碘基酮化合物30a-c或 35a-c為起始物，利用三氯化鋁 (AlCl3) 媒介誘導離子性環化反應，順利地得到高產率的螺旋雙環產物31a-c、32a-c及36a-c、37a-c。
另外，我們也利用溫度的不同成功地促使反應朝向單一位向產物進行，並可成功地控制產物的比例，得到高選擇性的結果。

Abstract

The main goal of the synthesis is to study the ionic cyclization reaction of α-iodo cycloalkanones bearing an allenic side chain. We prepared the α-iodocycloalkanones 30a-c and 35a-c as the stating materials developed in our laboratory ,then via the ionic cyclization reaction mediated by AlCl3. We can afford the spiro bicyclic products 31a-c, 32a-c, 36a-c and 37a-c in high yields successfully.

In addition, we force the reaction toward the single geometric products by controlling the temperature and we can successfully control the ratios of products with high yield.

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