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研究生: 廖英蘭
Liao, Ying-Lan
論文名稱: 寬射束電腦斷層輻射劑量的研究
Radiation Dosimetry of Wide Collimation Width Computed Tomography
指導教授: 莊克士
Chuang, Keh-Shih
蔡惠予
Tsai, Hui-Yu
口試委員: 田雨生
Yeu-Sheng Tyan
許靖涵
Ching-Han Hsu
許芳裕
Fang-Yuh Hsu
學位類別: 博士
Doctor
系所名稱: 原子科學院 - 生醫工程與環境科學系
Department of Biomedical Engineering and Environmental Sciences
論文出版年: 2014
畢業學年度: 102
語文別: 中文
論文頁數: 91
中文關鍵詞: 寬射束電腦斷層電腦斷層劑量指標平衡劑量套管游離腔輻射底片螺旋掃描動態體積掃描
外文關鍵詞: wide beam computed tomography, computed tomography dose index, equilibrium dose, thimble ionization chamber, radiochromic film, helical scan, dynamic wide volume scan
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  • 本研究目的為評估寬射束電腦斷層(computed tomography, CT)掃描儀的輻射劑量,研究分為三個部分:(1)傳統CT劑量指標(CT dose index, CTDI)在寬射束CT劑量低估情形並且建立不同劑量計的量測方法;(2)根據美國醫學物理師學會工作小組第111號報告,在320切CT掃描儀進行實驗,使用套管游離腔(thimble ionization chamber)與更長的CTDI假體串接,根據報告計算新的劑量指標:平衡劑量(equilibrium dose, )、平衡劑量–螺距比乘積(equilibrium dose-pitch product, )與平衡劑量常數(equilibrium dose constant, );(3)探討新的CT劑量最佳化技術,包含自動管電流調控(automatic tube current modulation, ATCM)、疊代演算法在劑量降低與雜訊抑低技術與新的動態體積掃描模式在臨床常規檢查的輻射劑量分佈情形。將寬射束電腦斷層輻射劑量的研究成果提供國內外相同研究領域的團隊作為參考依據,以期改善寬射束電腦斷層的劑量評估方法。


    The purpose of the study was to (1) estimate the amount of underestimation of radiation dose using conventional CT dose index theory; (2) to implement the methodology of wide beam CT dosimetry suggested by report of AAPM task group 111 on a 320-detector row CT scanner. The derived values of equilibrium dose, equilibrium dose-pitch product, and equilibrium dose constant and related dose indexes using a thimble ionization chamber and 600 mm length cylindrical phantom were provided as reference tables for users who has the same CT scanner. (3) to assess the radiation dose distribution of clinical CT examinations with latest CT dose and image quality optimization techniques which included automatic tube current modulation (ATCM) techniques, adaptive iterative dose reduction 3D (AIDR3D), and dynamic wide volume scan mode. The database of our study can be an reference for improving the radiation dose measurement for wide collimation width computed tomography.

    目錄 摘要 1 ABSTRACT 2 目錄 I 圖目錄 I 表目錄 I 第一章、前言 1 1-1電腦斷層的發展 1 1-2電腦斷層輻射劑量評估方法 3 1-3寬射束電腦斷層在現有的劑量評估系統限制 4 1-4電腦斷層掃描劑量降低方法 5 第二章、電腦斷層輻射劑量評估 8 2-1電腦斷層劑量原理與輻射劑量計 8 2-1-1電腦斷層劑量原理 8 2-1-2電腦斷層劑量假體與筆形游離腔 11 2-1-4電腦斷層輻射劑量計:輻射底片劑量計 13 2-2實驗方法與步驟 14 2-2-1電腦斷層劑量指標 14 2-2-2電腦斷層劑量分佈曲線 15 2-2-2-1套管游離腔方法 15 2-2-2-2輻射底片校正與劑量分佈量測 15 2-3實驗結果 16 2-3-1電腦斷層劑量指標 16 2-3-2電腦斷層劑量分佈曲線 21 2-3-2-1 XR-QA2底片的劑量反應曲線 21 2-3-2-2軸狀掃描劑量分佈 22 2-4討論 24 第三章、寬射束電腦斷層劑量指標 27 3-1理論架構 27 3-1-1寬射束電腦斷層劑量指標 27 3-1-2接近平衡函數推算平衡劑量的方法 33 3-1-3參考條件的平衡劑量、平衡劑量–螺距比乘積、平衡劑量常數與沈積劑量 34 3-1-4其他條件平衡劑量、平衡劑量–螺距比乘積與平衡劑量常數轉換方法 35 3-2實驗步驟 36 3-2-1寬射束電腦斷層掃瞄儀 36 3-2-2參考條件的寬射束電腦斷層劑量指標 36 3-2-3轉換其他條件的劑量指標 38 3-3實驗結果 39 3-3-1參考條件的寬射束電腦斷層劑量指標 39 3-3-2參考條件轉換其他條件的劑量指標 41 3-4討論 46 第四章、寬射束電腦斷層的臨床劑量評估 48 4-1前言 48 4-2寬射束電腦斷層技術發展 49 4-2-1自動管電流調控技術 49 4-2-2疊代演算雜訊抑低技術 51 4-2-3體積掃描模式 53 4-2-4器官劑量與有效劑量 54 4-2-4-1 ImPACT CT方法 55 4-2-4-3簡易推算有效劑量的方法 57 4-3實驗步驟 59 4-3-1自動管電流調控技術:螺旋掃描與體積掃描模式 59 4-3-2疊代演算雜訊抑低技術在動態體積掃描模式的比較 61 4-3-3常規成人檢查的表面劑量評估 63 4-3-4常規成人檢查的有效劑量 68 4-3-4-1 AAPM TG-111方法 68 4-3-4-2 ImPACT CT方法 68 4-3-4-3 CT-Expo方法 69 4-4實驗結果 70 4-4-1自動管電流調控技術:螺旋掃描與動態體積掃描模式 70 4-4-1-1動態體積掃描自動管電流調控與影像雜訊 70 4-4-1-2螺旋掃描自動管電流調控與影像雜訊 72 4-4-2動態體積掃描模式的疊代演算雜訊抑低技術 74 4-4-3常規成人檢查的表面劑量 79 4-4-4常規成人檢查的有效劑量 86 第五章、結論 87 未來工作 88 參考文獻 89 論文發表記錄 93

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