逐年增高的登革熱確定病例，對人類的生命安全造成極大的威脅。目前對登革熱主要的防治是利用噴灑農藥，但如此一來，不僅會造成登革熱病媒蚊－埃及斑蚊（Aedes aegypti）、白線斑蚊（Aedes albopictus）的抗藥性，也會造成環境的破壞。生物防治（biological control）是利用生物的獵食行為對要防治的生物進行捕食與掠殺。早在1981年即有研究指出，橈足類（Copepoda）會捕食蚊子的幼蟲，所以可做為防治登革熱病媒蚊的生物。本研究即是利用在新竹地區所採集到的劍水溞，進行實驗室與野外－新竹教育大學校區、新竹市十八尖山的實驗，以探討劍水溞捕食白線斑蚊幼蟲的能力。
實驗結果顯示在新竹地區水域所生長的溫中劍水溞（Mesocyclops thermocyclopoides）和北碚中劍水溞（Mesocyclops pehpeiensis）對白線斑蚊幼蟲的捕食能力沒有顯著的差異，但因劍水溞的體型僅有1~2mm，因此對剛孵化或孵化1天的白線斑蚊幼蟲捕食能力較好。另外，也發現當劍水溞或白線斑蚊幼蟲的密度提高時，劍水溞的捕食能力也相對提高了。進行野外實驗時，當實驗區的人口密度較高時，所收集到的白線斑蚊卵及幼蟲數量較高，但容器中如含有劍水溞，白線斑蚊幼蟲數量就會因劍水溞的捕食而有顯著性減少。可見，劍水溞的確適合做為病媒蚊的生物防治因子。

With the increasing numbers of confirmed cases of dengue infection year by year, life security of humans is under acute threat. At present, the primary prevention of dengue fever is the use of insecticide. However, it results in the insecticide resistance displayed by the vector of dengue, the Aedes aegypti and the Aedes albopictus, and the destruction of environment. Biological control is the treatment referred to the reduction of pest populations by natural predation. In 1981, there was a study stating that Copepoda would prey on larvae of mosquito and it can be treated as the prevention of the vector of dengue. This study aims to use Mesocyclops collected in Hsinchu area to launch a number of experiments set in the laboratory, National Hsinchu University of Education and Eighteen Peaks Mountain in Hsinchu City. It is to survey the predation ability of Mesocyclops preying on larvae of the Aedes albopictus .
The results of the experiments show that the predation ability of Mesocyclops thermocyclopoides Harada found in the sea in Hsinchu area is similar to it of Mesocyclops pehpeiensis Hu preying on larvae of the Aedes albopictus. Mesocyclops are typically one to two millimeters long. Hence, they have higher predation ability in preying on the larvae of the Aedes albopictus which are just hatched out or hatched out after one day. In addition, the findings indicate that the higher the density of Mesocyclops or larvae of the Aedes albopictus is, the better the predation ability of Mesocyclops becomes. In the field experiments, the evidence was shown that the amount of larvae of the Aedes albopictus will rise when the population density becomes higher in the area. However, if the containers store Mesocyclops, the amount of larvae of the Aedes albopictus will decrease significantly because of the predation of Mesocyclops. In conclusion, Mesocyclops can be one of the prevention factors of the vector of dengue fever.

王建平、廖國英。1998。湖泊中的浮游生物。科學月刊。第339期，195-202頁。
行政院衛生署疾病管制局。2009。登革熱防治工作指引。防疫學苑系列016。85頁。
吳輝秋、劉碧隆。2007。認識蚊子與登革熱。高雄縣醫師會誌。第24期，16-23頁。
沈嘉瑞、戴愛云、張崇洲、李志英、宋大祥、宋玉枝、陳國孝。1979。中國動物誌-淡水橈足類。科學出版社。北京。450頁。
徐爾烈。2007。登革熱病媒蚊生態分布與調查防治。行政院環境保護署。登革熱病媒防治班講義。9頁。
陳非洲、郭曉鳴、劉正文。2008。中國中劍水溞屬種類記述。四川動物。第27卷第1期，55-62頁。
陳菁惠。2007。高雄縣某國中學生登革熱防治知識、態度、預防行為及相關因素之研究。國立臺灣師範大學衛生教育學系研究所碩士論文。159頁。
黃志傑、李翠瓊、邱鴻英、吳炳輝。2005。2004年台灣地區登革熱疫情防治報告。疫情報導。第21卷 第06 期。23頁。
葉曉菁。2000。台南七股潟湖區及附近海域浮游橈足類的種類組成、分布及其攝食研究。國立中山大學海洋資源研究所碩士論文。87頁。

Bonnet, D.D. and T. Mukaida. 1957. A copepod predaceous on mosquito larvae. Mosq. News, 17:99–100.
Brian,H.K., V.S. Nam, T.V. Tien, N.T. Yen, T.V. Phong, V.T. Diep, T.U. Ninh, A.Bektas, and J-J. Aaskov. 2002. Control of Aedes vectors of dengue in three provinces of Vietnam by use of Mesocyclops (copepoda) and community-based methods validated by entomologic, clinical, and serological surveillance. Am. J. Trop. Med. Hyg., 66(1)：40–48.
Brown, M.D., D.O. Walker, J.K. Hendrikz, C.P. Cabral, D.B. Araujo, Z.M. Ribeiro, and B.H. Kay. 1994. Chlorine tolerance of Mesocyclops (Cyclopoida: Cyclopidae) copepods and three container-breeding species of mosquitoes. Environ. Entomol., 23:1245–1249.
Daniels, C.W. 1901. Reports of the Malaria Commission of the Royal Society, Series. 5:28–33.
Gerardo, A.M., V.M. Maria, A.C. Scorsetti, and L. Gerardo. 2004. Evaluation of Mesocyclops annulatus (Copepoda: Cyclopoidea) as a Control Agent of Aedes aegypti (Diptera: Culicidae) in Argentina. Mem Inst Oswaldo Cruz, Rio de Janeiro, (5): 535-540.
Gionar,Y.R., S. Atmosoedjono, and M.J. Bangs. 2006. Mesocyclops brevisetosus (cyclopoida: cyclopoidae) as a potential biological control agent against mosquito larvae in Indonesia. J. Am. Mosq. Cont. Assoc., 22(3):437–443.
Hurlbut, H.S. 1938. Copepod observed preying on first instar larva of Anopheles quadrimaculatus. J. Parasitol., 24:281.
Kumar,R. and J.-S. Hwang. 2006. Larvicidal efficiency of aquatic predators: A perspective for mosquito biocontrol. Zool. Stud., 45(4): 447-466.

Lewis, D.J. 1932. The mosquitoes of Wicken Fen. In:Gardiner JS, ed. The Natural History of Wicken Fen,Part VI. Cambridge, United Kingdom. Bowes and Bowes, pp.548–559.
Lindberg, K. 1949. Crustace´s Cope´podes comme ennemis naturels de larves d’anophe`les. [Copepod crustaceans as natural enemies of Anopheles larvae.]. Bull. Soc. Pathol. Exot., 42:178–179.
María, V.M., M. Gerardo, and J-J García. 2002. Laboratory Evaluation of Mesocyclops annulatus (Wierzejski, 1892) (Copepoda: Cyclopidea) as a Predator of Container-breeding Mosquitoes in Argentina. Mem. Inst. Oswaldo Cruz, Rio de Janeiro, (6): 835-838.
Marten, G.G. and J-W. Reid. 2007. Cyclopoid copepods. Biorational Control of Mosquitoes. Am. Mosq. Cont. Assoc. Bull., 7：65-92.
Marten, G.G. 1984. Impact of the copepod Mesocyclops leuckarti pilosa and the green alga Kirchneriella irregularis upon larval Aedes albopictus (Diptera:Culicidae). Bull. Soc. Vector. Ecol., 9:1–5.
Marten, G.G. 1990. Evaluation of cyclopoid copepods for Aedes albopictus control in tires. J. Am. Mosq. Cont. Assoc., 6:681–688.
Marten, G.G., G. Borjas, M. Cush, E. Ferna´ndez, and J-W. Reid. 1994. Control of larval Ae. aegypti (Diptera:Culicidae) by cyclopoid copepods in peridomestic breeding containers. J. Med. Entomol., 31:36–44.
Marten,G., M. Nguyen,G. Thompson, and E. Bordes. 1997. Copepod Production & Application for Mosquito Control. New Orleans Mosquito Control Board. pp.40.
Marten,G.G. 1989. A survey of cyclopoid copepods for control of Aedes albopictus larvae. Bull. Soc. Vector. Ecol., 14:232–236.
Phong, T.V., N. Tuno, H. Kawada, and M. Takagi. 2008. Comparative evaluation of fecundity and survivorship of six copepod (Copepoda: Cyclopidae) species, in relation to selection of candidate biological control agents against Aedes aegypti. J. Am. Mosq. Cont. Assoc., 24:61- 69.
Rey, J.R., S. O´Connell, S. Suárez, Z. Menéndez, L.P. Lounibos, and G. Byer. 2004. Laboratory and field studies of Macrocyclops albidus (Crustacea:Copepoda) for biological control of mosquitoes in artificial containers in a subtropical environment. J. Vect. Ecol., 29:124–134.
Rivie`re, F. and R. Thirel. 1981. La pre´dation du cope´pode Mesocyclops leuckarti pilosa (Crustacea) sur les larves de Aedes Stegomyia) aegypti et Ae. (St.) polynesiensis (Dip.: Culicidae): essais pre´liminaires d’utilisation comme agent de lutte biologique. [Predation of the copepod Mesocyclops leuckarti pilosa (Crustacea) on the larvae of Aedes (Stegomyia) aegypti and Ae. (St.) polynesiensis (Dip.: Culicidae): preliminary trials of its use as a biological control agent.]. Entomophaga, 26:427–439.
Ueda, H. and J.W. Reid（eds）. 2003. Copepoda：Cyclopoida Genera Mesocyclops and Thermocyclops；Guides to the Identification of the Microinvertebrates of the Continental Waters of the World No.20. Coordinating editor：H. J. F. Dumont. pp.318.