此平台利用生物化學能驅動微流體而組織結構能提供最原始心臟的收縮舒張之生物力學模型，本研究的突破在於將心肌細胞一維方向的收縮舒張性質藉由支架結構的建立轉變成三維性質之力學響應，而能提供生物心肌細胞之收縮舒張應力、壓力、流量變化、質傳能力等等，為模擬真實心臟質傳系統的生理環境。
本實驗有兩種主導方式來規範細胞生長取向，基材幾何主導(Geometric dominate)和製程扭曲主導(liquid rope coiling dominate)，兩種主導方式來自於調控製程的流道大小的配比、流體黏製係數、流量等相關參數。基材幾何主導是在二維彎曲的平面系統下成長，會因為彎曲的程度不同，進而影響到細胞成長的取向。製程扭曲主導是製程中的水膠管因在固化溶液中進行穩定的動態平衡，捲繞將對水膠管產生彎曲及扭轉等應力，經固化的過程把殘留表面的應力給記憶起來，表面具有應力應變的次微結構。當捲繞性越強時，能產生的應力應變也越強，使起產生沿著扭曲方向的次微結構。
搭配兩種主導細胞生長的方是和水膠分離技術能在不傷害細胞，其離子濃度相當於正常人體血管的環境下分離水膠管，分離後結構完整，並且保有原本細胞功能，建構心肌纖維組織管並且能穩定提供0.35Hz的作動頻率。

This platform utilizes biochemical energy to drive microfluidics and the tissue structure provides the biomechanical model of systolic and relaxation of the primitive heart tube. This study is to transform the systolic and diastolic properties of myocardial cells in one dimension by three-dimensional properties that the mechanical response can provide the systolic and diastolic stress, pressure, flow change, quality transfer ability of the cardiomyocytes, etc., to simulate the physiological environment of the real heart circulatory system.
There are two main ways to regulate cell growth orientation, the geometric dominate and the liquid rope coiling dominate. The two dominant methods are the ratio of the flow path size of the control process, fluid viscosity, and flow rate. The two dominant methods are controlled by the flow channel size, fluid viscosity, flow rate and other related parameters of the control process.
The geometry of the substrate is dominated by a two-dimensional curved planar system, which affects the orientation of cell growth due to the degree of bending.
The fabrication process is the stable dynamic balance of the hydrogel in the curing process. The coiling process will cause bending and torsion stress on the hydrogel. The curing process will memorize the residual surface stress and the surface has a stress-strained sub-microstructure. The stronger coiling, the stronger strain that be generated, resulting in the generation of sub-microstructures along the twisting direction.

The combination of the two dominant cell growth methods and the hydrogel separation can separate the hydrogel without damaging the cells, and the ion concentration is equivalent to the normal human blood vessel. After separation, the structure is intact, and the original cell function is preserved, and the myocardial fiber tissue is constructed and the pumping frequency of 0.35 Hz that be stably provided.

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