本論文旨在利用混合不同的陽離子與非離子界面活性劑合成新穎的中孔洞二氧化矽奈米顆粒，並透過調整合成條件，例如改變界面活性劑的莫耳分率、合成溫度、濃度、pH值、矽源的注射速度、使用不同的矽源和加入乙醇添加物等，來控制所合成奈米顆粒的結構、形貌和大小，並透過X光粉末繞射儀、氣體物理吸脫附儀、掃描式和穿透式電子顯微鏡對所合成的奈米顆粒進行分析。其中，我們成功的合成出具有c2mm結構且孔洞截面為橢圓形的中孔洞二氧化矽奈米顆粒MMT-1，且此中孔洞二氧化矽奈米顆粒還具有螺旋孔道的特性，另外，我們除了可對其結構和大小進行調控外，還可調控其型貌為均一的球狀顆粒或是單軸奈米棒。最後，我們還合成出具有Ia3d結構的中空球狀奈米顆粒，利用Ia3d三維直通的孔道和中空球狀顆粒的高孔體積，未來在生物醫學方面極具發展潛力。

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