研究生: |
白崢鈺 |
---|---|
論文名稱: |
二氧化鈦奈米粒子對色胺酸吸附動力學研究 Adsorption Kinetics of Tryptophan on TiO2 Nanoparticles |
指導教授: | 吳劍侯 |
口試委員: | |
學位類別: |
碩士 Master |
系所名稱: |
原子科學院 - 生醫工程與環境科學系 Department of Biomedical Engineering and Environmental Sciences |
論文出版年: | 2010 |
畢業學年度: | 98 |
語文別: | 中文 |
論文頁數: | 64 |
中文關鍵詞: | TiO2 、Tryptophan 、UV光照 、濕度 、Langmuir吸附等溫模式 |
外文關鍵詞: | TiO2, Tryptophan, UV illumination, humidity, Langmuir adsorption |
相關次數: | 點閱:2 下載:0 |
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二氧化鈦(TiO2)近幾年來在醫學或生命科學領域廣泛的發展,例如癌症細胞或抗菌等的治療,此奈米物質同時也具有生物相容性。然而針對生物分子的基本吸附或照光光降解等基本機制尚未完全了解,因此本研究主要探討紫外光光照改變TiO2表面特性與其吸附胺基酸之吸附反應動力關係。
本研究主要分成兩部分,第一部分為利用UVA (352 nm)、UVB (313 nm)、及UVC (254 nm)等不同波長燈管為光源,並改變照光環境中的濕度,進行TiO2的照光處理。第二部分為使用不同條件下處理的TiO2,於不同pH值及相對濕度(RH)下探討色胺酸(Tryptophan)吸附於TiO2表面之影響,再以Langmuir吸附等溫模式模擬求得等溫吸附常數(Kads)。研究中利用動態光散射儀(DLS)量測TiO2水合粒徑與介面電位變化及利用螢光光譜儀測定色胺酸溶液吸附量變化,並進一步討論TiO2在懸浮液中的分散穩定性與吸附反應動力。
結果顯示紫外光光照波長越短(UVC)可使TiO2水合粒徑明顯下降,介達電位明顯上升,若增加照光環境中的濕度則會有助於表面Ti-OH基的形成,等電點往鹼性pH值位移,另外發現進行Tryptophan吸附時,容易造成TiO2的不穩定而粒子聚集嚴重,但若在使用高濕度照光下的TiO2進行吸附,則過程中TiO2均穩定存在,且最終飽和吸附量明顯增加。本研究最後也使用Tryptamine、indole、1,2,3,4-Tetrahydroquinoline和aspartic acid等幾種化合物進行吸附,藉以推測Tryptophan在不同pH值下的吸附機制。
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