本篇論文欲探討方向可以分成兩個部分，首先回顧 Jost (2008) 針對一般常用的基因多樣性指標 GST (Wright, 1943 and 1951) 的修正為 D 指標(Jost, 2008) 的作法，並討論 Jost (2008) 引用 Nei & Chesser (1983) 與 Chao et al. (2008) 的估計方法
的差異性與關聯性，與其修正估計量。而本文主要的研究方向是將多樣性指標 D 推廣成 DqN 指標族，給予 DqN 指標族與生物多樣性之間一個充要條件的證明，該證明指出，在適當的條件下，只要考慮有限個 DqN 指標，便有充分的訊息來表達生物多樣性。對於 DqN 指標的估計，則是將韓若平(2008) 與 Chao et al. (2008) 的估計想法當做引子，依續修正估計量方法的想法，再提出一般化的 D1N_htc 與 DqN_adj 估計量，並利用電腦模擬試驗的方式，得到 D1N_htc 與 DqN_adj 估計量在小樣本的情況下，不論在偏誤或均方根誤差的表現上，都優於之前的估計方法。在實例分析中，取用線上資料庫 ALFRED (http://alfred.med.yale.edu ) 所提供的人體
在某些基因座上的等位基因相對頻率的資料，並採用這些資料以應用本篇論文所討論的多樣性指標族 DqN 來比較不同的人種間，在不同染色體或不同基因座上的多樣性或差異性。

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