細胞分裂週期是探索癌症細胞運作機制的重要線索，所以研究癌症細胞的基因調控網路是依個相當重要的研究主題。由於目前癌症的生物基因晶片基因表現資料已經可以取得，所以我們希望藉由這些基因表現資料來建立一個動態模型模擬癌症細胞分裂週期的基因調控網路，並藉由動態基因調控網路更加了解癌症細胞分裂週期的調控機制所不為人知的一面。完成上述動態模型及建構基因調控網路之後，我們會更進一步的討論關鍵的調控指在網路中的調控能力以及在調控網路中所扮演的角色。
藉者生物晶片的基因表現資料建立動態模型，我們必須先靠相關系數的檢測找出被調控的目標基因上游的調控基因，再藉由上游調控基因建立主要的基因調控方程式。找出調控方程式建立好動態模型之後，我們就可以在目標基因及上游調控基因之間描繪出基因間的調控網路，然後再把上由調控基因設定為目標基因，繼續往上有檢測調控基因並建立起調控方程式。
如此一來，我們將可以在每個目標基因及上游調控基因之間建立龐大且複雜的癌症細胞分裂週期基因調控網路，並更加了解內部機制。
最後，靠者複雜的動態調控網路，我們可以討論網路中的每個調控基因的調控能力之強弱以及在癌症細胞分裂基因調控網路中是否扮演重要的角色。

Cell cycle is an important clue to unravel the mechanism of cancer cells. Therefore, it is important topic to study the gene regulatory network of cancer cell cycle. Recently, expression profiles of cDNA microarray data of cancer cell cycle are available. Therefore, it is more appealing to construct a dynamic model for gene regulatory network of cancer cell cycle to gain more insight into the infrastructure of gene regulatory mechanism of cancer cell via microarray data. Then, based on the dynamic model, we will discuss the regulatory abilities of regulatory genes to find their roles in the network.
A dynamic model is proposed for the gene regulatory network of cancer cell cycle. Based on the gene regulatory dynamic model and the cDNA expression profiles of the target gene, the regulatory function from upstream regulators is detected by a correlation algorithm to trace back their upstream regulatory genes.　 Then we can construct the regulatory network between target genes and their upstream regulatory genes by identifying the chemical kinetic parameters of regulatory pathways via the cDNA expression profiles of the target genes and their upstream regulatory genes. Then these upstream regulatory genes are considered as target genes. 　We trace back their upstream regulatory genes. Iteratively, we will construct the whole dynamic gene regulatory network of cancer cell cycle which is useful to gain more insight into the whole mechanism of cancer cell. Finally, based on the dynamic regulatory network, we analyze the regulatory abilities of regulatory genes to discuss their roles in the network of cancer cell cycle.

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