近年，因為奈米科技在各領域擁有近乎無限地發展可能引起了各領域的科學家很大的注意，如生物感測器、奈米大小的電路、磁性半導奈米線、量子點1,2…等。
此方面的研究將可提供我們應用在下一世代的電子、光學、及磁性材料與裝置。
TSB長久以來其對高劑量的的輻射造成的DNA斷裂傷害耐受性一直是被研究的焦點6；除了輻射抗性外、TSB菌尚有其他特殊的性質，如錳致細胞再分裂8（Manganese-induced dell division）、厚細胞膜及細胞外膜（outer membrane）、鹽引發細胞多聯7(multi-cell forming)…等現象。本篇論文將先前本實驗室所發現的另一極為特殊之現象耐輻射奇異球菌引發之奈米銀線合成做更進一步的闡述。
耐輻射奇異球菌在靜止期後，會分泌出某些特殊的成分能將銀離子轉化還原成大量的奈米級結構線狀的還原狀態，我們認為此分泌出之成分為胜肽。
藉由利用相關的蛋白質分析純化儀器HPLC等，能協助我們將此蛋白質分離出進行進一步的分析應用，再利用共軛焦顯微鏡、穿透式電子顯微鏡的協助下，提供我們對此現象背後的的原理及其在生物上的意義更詳盡的知識，並利用此結果將生物科技應用在奈米科技上。

Nanotechnology has drown great attention for it’s limitless application in various field like bio-sensors, nano-circuit, magnetic and semi-conducting nano-wires, quantum-dots etc. Investigations in this area may provide us an opportunity to incorporate it into next generation electronic, optical and magnetic materials and devices. Deinococcus rediodurans has long been studied for it’s extremely resistance against acute radiation damage which produces lethal DNA double strand breaks(DSB) within cells. Despite strong radiation resistance, Deinococcus rediodurans has several unique traits such as Mn induce cell division, thick cell wall with outer membrane, salt-mediate multi-cell formation etc. In this thesis we report another extraordinary phenomena from this bacteria which is previously undiscovered. Deinococcus rediodurans is able to produce mass amount of silver nanostructure under certain condition. We believe that Deinococcus rediodurans produces specific peptide for this activity. By using HPLC purification we’ve been able to identify this peptide. After purification we further investigate it’s molecular weight. With help from confocal microscopy and transmission emission microscopy which provide us more data in details for further exanimation of the mechanism behind this bio-inspired silver nano-wire synthesis and hopefully applies biotechnology into nano-science.

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