隨著人類平均壽命增加，使全球步入高齡化社會，罹患慢性病的人口也日漸增加，根據衛生署統計全台灣有將近一千零二十萬的慢性病患，且全台十大死因當中有九個為慢性病所導致。相關醫療照護問題及醫院、藥局之間的合作關係接連出現新挑戰，除了透過醫療技術、飲食作息來改善慢性疾病症狀外，亦需探索創新的服務設計來改善問題。
新穎的醫療技術雖然成功地延長了人類的壽命，但是慢性病患者的日常用藥仍存在許多問題。根據世界衛生組織統計，僅30%~60%的慢性病患者有確實遵照醫生囑咐服用藥物，其低下的用藥依從性將增加罹患併發症的風險，或是加速病況惡化，亦為將來的醫療照護體系造成更多財務負擔。傳統的用藥方式例如：藥袋、藥盒或提醒方式易讓患者產生焦慮不安、處於弱者的負面心態。有神經質人格特質的患者較容易感覺到壓力、緊張、焦慮的情緒，或是表達未有明確醫療證據的身體不適感或長期或複雜的用藥過程中感覺到挫折、較容易擔心藥品的副作用，因此導致錯過或忽略正確的用藥時間，間接影響醫療效果不彰或患者的生活信心下降。
傳統的用藥干預實驗著重研究「衛生教育、簡化用藥方案或是相關照護者介入」對依從性的影響，較少從人格特質的面向切入。本研究透過深度訪談了解病患者的用藥現況及體驗，經過質性分析整理出四大主題，包含基本病理資訊、低用藥依從性之原因、藥品管理習慣及生活型態。另外參考說服科技（Persuasive Technology）及心理學中的自我肯定理論（Self-affirmation）架構，針對具有神經質人格特質之患者設計用藥提醒訊息，並招募參與者進行干預實驗。透過 LINE 接收提醒訊息，於測後訪談中採用卡片分類法，了解其對訊息的理解邏輯、激勵患者用藥依從性的動力來源，並歸納有效訊息的重點元素，包含提及正向的價值觀、個人角色、社會關係等概念，較能喚起參與者對自我形象完整保護。本研究的結果，跳脫出傳統衛教知識的干預內容，能作為未來用藥提醒訊息設計的切入參考。

According to the statistics of the National Health Insurance Department, nearly 10.2 million people have a chronic illness in Taiwan. Other surprising numbers from the World Health Organization (WHO), only 30%-60% of patients follow treatment instruction. A low adherence rate on medication might accelerate illness deterioration and increase the financial burden on the health care system. Traditional treatment and intake, such as medicine bags, pillboxes or monotonous reminders, can easily cause anxious or negative emotion, and indirectly lead to poor medical effects.
In previous studies, researchers often focused on education or simplify the medication regimens, less from the perspective of personality traits. Therefore, what kind of design principles are most effective for interventions are yet to be tested in multiple chronic conditions.
In this study, we firstly investigated the medication intake behavior by deep-interview and aggregated into four categories, including pathological information, causes of low adherence rate, medication management behavior, and lifestyle. Secondly, designed the reminders for patients who have neuroticism personality traits based on persuasive technology and self-affirmation theory. Third, by sending a variety of persuasive messages for fourteen days. A post-test interview and card-sorting are conducted to understand what kind of messages could better motivate behavior. When messages convey the meaning of values, individual roles, social relationships could arouse patients’ responses to protect self-integrity. The result of this study is different from the traditional intervention design,it offers guidelines for future reminders design.

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