研究生: |
陳紹弘 Chen, Shao-Hong |
---|---|
論文名稱: |
生物鈉鈣離子通道交換機制之探討 A Study of the Sodium Calcium Ion Exchange Mechanism in NCX |
指導教授: |
劉晉良
Liu, Jinn-Liang |
口試委員: | |
學位類別: |
碩士 Master |
系所名稱: |
南大校區系所調整院務中心 - 應用數學系所 應用數學系所(English) |
論文出版年: | 2015 |
畢業學年度: | 103 |
語文別: | 中文 |
論文頁數: | 30 |
中文關鍵詞: | 鈉鈣離子交換通道 、分子動力模擬 、離子通道 |
外文關鍵詞: | NCX_Mj, VMD, ion channels |
相關次數: | 點閱:3 下載:0 |
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生物細胞鈉鈣離子交換通道,是以極快的速度讓鈣離子由細胞內與鈉離子交換至細胞外。本研究利用Poisson-Fermi之理論分析NCX(sodium calcium exchanger)之離子結合構造,使我們能夠以數學的方式探討鈉鈣離子在NCX的交換機制,並成功的解釋鈉鈣離子交換之實驗結果。
Biological sodium calcium ion exchange channel (NCX) removes calcium ions very rapidly from cell inside in exchange with sodium ions from outside. The Poisson-Fermi theory is used to analyze the binding potentials of NCX. It allows us to mathematically investigate the sodium-calcium ion exchange mechanism in NCX. Numerical results have been shown to agree with the experimental results of the sodium-calcium ion exchange.
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