研究生: |
林瑩兒 Lin, Ying-Er |
---|---|
論文名稱: |
ERAD相關基因derlin-1之功能分析 Functional analysis of ERAD gene derlin-1 |
指導教授: |
桑自剛
Sang, Tzu-Kang |
口試委員: | |
學位類別: |
碩士 Master |
系所名稱: |
生命科學暨醫學院 - 生物科技研究所 Biotechnology |
論文出版年: | 2009 |
畢業學年度: | 97 |
語文別: | 英文 |
論文頁數: | 45 |
中文關鍵詞: | 功能分析 |
相關次數: | 點閱:2 下載:0 |
分享至: |
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Reference
Braun, S., K. Matuschewski, et al. (2002). "Role of the ubiquitin-selective CDC48(UFD1/NPL4 )chaperone (segregase) in ERAD of OLE1 and other substrates." EMBO J 21(4): 615-21.
Chang, H. Y. and D. F. Ready (2000). "Rescue of photoreceptor degeneration in rhodopsin-null Drosophila mutants by activated Rac1." Science 290(5498): 1978-80.
Crawshaw, S. G., B. C. Cross, et al. (2007). "The oligomeric state of Derlin-1 is modulated by endoplasmic reticulum stress." Mol Membr Biol 24(2): 113-20.
Deshaies, R. J., S. L. Sanders, et al. (1991). "Assembly of yeast Sec proteins involved in translocation into the endoplasmic reticulum into a membrane-bound multisubunit complex." Nature 349(6312): 806-8.
Gillece, P., J. M. Luz, et al. (1999). "Export of a cysteine-free misfolded secretory protein from the endoplasmic reticulum for degradation requires interaction with protein disulfide isomerase." J Cell Biol 147(7): 1443-56.
Hebert, D. N. and M. Molinari (2007). "In and out of the ER: protein folding, quality control, degradation, and related human diseases." Physiol Rev 87(4): 1377-408.
Jensen, T. J., M. A. Loo, et al. (1995). "Multiple proteolytic systems, including the proteasome, contribute to CFTR processing." Cell 83(1): 129-35.
Kawaguchi, S. and D. T. Ng (2007). "SnapShot: ER-associated protein degradation pathways." Cell 129(6): 1230.
Knop, M., A. Finger, et al. (1996). "Der1, a novel protein specifically required for endoplasmic reticulum degradation in yeast." EMBO J 15(4): 753-63.
Kondo, H., C. Rabouille, et al. (1997). "p47 is a cofactor for p97-mediated membrane fusion." Nature 388(6637): 75-8.
Kopito, R. R. (1997). "ER quality control: the cytoplasmic connection." Cell 88(4): 427-30.
Lilley, B. N. and H. L. Ploegh (2004). "A membrane protein required for dislocation of misfolded proteins from the ER." Nature 429(6994): 834-40.
Matlack, K. E., W. Mothes, et al. (1998). "Protein translocation: tunnel vision." Cell 92(3): 381-90.
McCracken, A. A. and J. L. Brodsky (1996). "Assembly of ER-associated protein degradation in vitro: dependence on cytosol, calnexin, and ATP." J Cell Biol 132(3): 291-8.
McCracken, A. A. and J. L. Brodsky (2005). "Recognition and delivery of ERAD substrates to the proteasome and alternative paths for cell survival." Curr Top Microbiol Immunol 300: 17-40.
Meusser, B., C. Hirsch, et al. (2005). "ERAD: the long road to destruction." Nat Cell Biol 7(8): 766-72.
Meyer, H. H., H. Kondo, et al. (1998). "The p47 co-factor regulates the ATPase activity of the membrane fusion protein, p97." FEBS Lett 437(3): 255-7.
Meyer, H. H., J. G. Shorter, et al. (2000). "A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways." EMBO J 19(10): 2181-92.
Meyer, H. H., Y. Wang, et al. (2002). "Direct binding of ubiquitin conjugates by the mammalian p97 adaptor complexes, p47 and Ufd1-Npl4." EMBO J 21(21): 5645-52.
Molinari, M., V. Calanca, et al. (2003). "Role of EDEM in the release of misfolded glycoproteins from the calnexin cycle." Science 299(5611): 1397-400.
Nakatsukasa, K. and J. L. Brodsky (2008). "The recognition and retrotranslocation of misfolded proteins from the endoplasmic reticulum." Traffic 9(6): 861-70.
Nishitoh, H., H. Kadowaki, et al. (2008). "ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1." Genes Dev 22(11): 1451-64.
Oda, Y., N. Hosokawa, et al. (2003). "EDEM as an acceptor of terminally misfolded glycoproteins released from calnexin." Science 299(5611): 1394-7.
Oda, Y., T. Okada, et al. (2006). "Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation." J Cell Biol 172(3): 383-93.
Patel, S. and M. Latterich (1998). "The AAA team: related ATPases with diverse functions." Trends Cell Biol 8(2): 65-71.
Plongthongkum, N., N. Kullawong, et al. (2007). "Ire1 regulated XBP1 mRNA splicing is essential for the unfolded protein response (UPR) in Drosophila melanogaster." Biochem Biophys Res Commun 354(3): 789-94.
Ran, Y., H. Hu, et al. (2008). "Derlin-1 is overexpressed on the tumor cell surface and enables antibody-mediated tumor targeting therapy." Clin Cancer Res 14(20): 6538-45.
Ryoo, H. D., P. M. Domingos, et al. (2007). "Unfolded protein response in a Drosophila model for retinal degeneration." EMBO J 26(1): 242-52.
Sang, T. K. and D. F. Ready (2002). "Eyes closed, a Drosophila p47 homolog, is essential for photoreceptor morphogenesis." Development 129(1): 143-54.
Sayeed, A. and D. T. Ng (2005). "Search and destroy: ER quality control and ER-associated protein degradation." Crit Rev Biochem Mol Biol 40(2): 75-91.
Sun, F., R. Zhang, et al. (2006). "Derlin-1 promotes the efficient degradation of the cystic fibrosis transmembrane conductance regulator (CFTR) and CFTR folding mutants." J Biol Chem 281(48): 36856-63.
Taxis, C., R. Hitt, et al. (2003). "Use of modular substrates demonstrates mechanistic diversity and reveals differences in chaperone requirement of ERAD." J Biol Chem 278(38): 35903-13.
Tomlinson, A. and D. F. Ready (1987). "Cell fate in the Drosophila ommatidium." Dev Biol 123(1): 264-75.
Tomlinson, A. and D. F. Ready (1987). "Neuronal differentiation in Drosophila ommatidium." Dev Biol 120(2): 366-76.
Tsai, B., C. Rodighiero, et al. (2001). "Protein disulfide isomerase acts as a redox-dependent chaperone to unfold cholera toxin." Cell 104(6): 937-48.
Tsai, B., Y. Ye, et al. (2002). "Retro-translocation of proteins from the endoplasmic reticulum into the cytosol." Nat Rev Mol Cell Biol 3(4): 246-55.
Vembar, S. S. and J. L. Brodsky (2008). "One step at a time: endoplasmic reticulum-associated degradation." Nat Rev Mol Cell Biol 9(12): 944-57.
Wang, J., H. Hua, et al. (2008). "Derlin-1 is overexpressed in human breast carcinoma and protects cancer cells from endoplasmic reticulum stress-induced apoptosis." Breast Cancer Res 10(1): R7.
Wang, Q. and A. Chang (2003). "Substrate recognition in ER-associated degradation mediated by Eps1, a member of the protein disulfide isomerase family." EMBO J 22(15): 3792-802.
Ward, C. L., S. Omura, et al. (1995). "Degradation of CFTR by the ubiquitin-proteasome pathway." Cell 83(1): 121-7.
Wolff, T. and D. F. Ready (1991). "The beginning of pattern formation in the Drosophila compound eye: the morphogenetic furrow and the second mitotic wave." Development 113(3): 841-50.
Ye, Y., H. H. Meyer, et al. (2001). "The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol." Nature 414(6864): 652-6.
Ye, Y., Y. Shibata, et al. (2004). "A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol." Nature 429(6994): 841-7.
Zhang, X., A. Shaw, et al. (2000). "Structure of the AAA ATPase p97." Mol Cell 6(6): 1473-84.