摘要
本研究探討家長與個案之知識行為態度如何影響其成長。一共三位個案，進行半結構式訪談並將訪談資料進行內容分析，透過系統性文獻探討與敍事探究，分析資料後結果顯示：
個案一是自閉症類群障礙者 (ASD) 透過長期規律的爬山運動，享受著森林浴帶來的療育效果，改善睡眠品質，調節神經系統與免疫力，進而也提升認知能力和情緒穩定度。另一方面也提高食慾，能接受更多元的食物種類，進而增強體力和肌肉量。這體現了運動、睡眠和營養三者缺一不可的重要性。
個案二是注意力不足過動症 (ADHD)的成人，在強烈病識感趨使下，她自我覺知生理與心理方面疑似有ADHD症狀，主動尋找相關資訊，透過就醫服藥提升專注力，且藉由拳擊運動抒發內心的焦躁感，以及多蔬果但少食加工食品，藉由蔬果中的植化素提高體內抗氧化的儲備能力，降低慢性發炎狀態，舒緩ADHD症狀。
個案三是有著自閉症、注意力不足過動症和妥瑞症等共病症的小孩。他的巧克力測試顯示，複雜的食品添加物和過多的糖分攝取會加重過動症狀，但在特意避食耐受性不好的食物成分，症狀就得到舒緩。並在透過生活習慣的修正、就醫服藥控制症狀、減少攝取精緻碳水化合物和加工食品，妥瑞症得以緩解。由以上2個個案觀察到食物成分對個案症狀有諸多的影響，應加強個別化的營養需求，做最佳的飲食型態調整，再加上個別化的營養補充劑，提升生活品質，這是一輩子的重要課題。
家庭支持與環境中的他人對特殊兒之理解和鼓勵深遠地影響個案的自我接納和後續的自我實現及人際關係。
關鍵詞：睡眠、飲食型態、爬山運動、森林浴

Abstract
This study explores the influence of parental knowledge, behaviors, and attitudes on child development. Semi-structured interviews with three subjects were analyzed using content analysis, systematic literature review, and narrative inquiry.
Case 1 involves an individual with Autism Spectrum Disorder (ASD) benefiting from long-term, regular exercise, specifically mountain climbing. The therapeutic effects of forest bathing improve sleep quality, regulate the nervous system and immunity, boost cognitive abilities and emotional stability, increase appetite and physical strength. This underscores the interaction of exercise, sleep, and nutrition.
Case 2 focuses on an adult with Attention Deficit Hyperactivity Disorder (ADHD) who recognized her symptoms and sought medical treatment. Medication improved her focus, and boxing alleviated restlessness. A diet rich in fruits and vegetables, low in processed foods, increased her antioxidant reserves, reduced chronic inflammation, and alleviated ADHD symptoms.
Case 3 describes a child with autism, ADHD, and Tourette syndrome. Complex food additives and excessive sugar intake exacerbated hyperactivity, as shown by a chocolate test. Avoiding poorly tolerated food ingredients and reducing refined carbohydrates and processed foods alleviated symptoms of Tourette syndrome.
The last two cases highlight the significant impact of food components on symptoms and emphasizes the need for individualized dietary patterns and personalized supplements. Family support and encouragement significantly influence self-acceptance, self-realization, and interpersonal relationships.

Keywords: sleep, dietary patterns, mountain climbing, forest bathing

參考文獻
一、 中文部分
Aaron H. (2019年3月16日)。如果「利他能」不是聰明藥，那它的作用是什麼？又為何有這樣的誤會？https://pansci.asia/archives/156172
Dr. med. Anne Fleck. (2020)。脂肪的療癒力—從預防到治療，全面對抗疾病、老化、情緒的革命性營養新知〔彭意梅譯〕。商週出版。
Dr. med. Ulrich Strunz. (2021)。大腦不老身體就好〔黃淑欣譯〕。商週出版。（原著出版於2020年）。頁250-252。
Matthew Walker. (2019)。為什麼要睡覺？睡出健康與學習力、夢出創意的新科學〔姚若潔譯〕。天下文化出版。（原著出版於2017年）。
Natasha Campbell-McBride. (2018)。改善情緒障礙的腸道食療聖經〔陳莉淋譯〕。采實文化出版。（原著出版於 2010 年）。
Scott C. Anderson, John F. Cryan, Ted Dynan. (2019)。精神益生菌〔王惟芬譯〕。大石文化。（原著出版於2017年）。
Susan S. Blum, Michele Bender. (2023)。免疫系統全方位復原計畫：從飲食、壓力、腸道、肝臟四大途徑全面拯救你的免疫系統〔毛佩琦譯，第二版〕。如果出版社。
William J. Walsh. (2016)。營養的力量 〔蘇聖傑醫師譯〕。博雅智庫。（原著出版於 2014 年）。
William Shaw. (2008)。自閉症生物療法 〔歐忠儒譯〕。元氣齋。（原著出版於 2004 年）。
王升陽、陳啟榮、林昱德、賴建興、謝瑀心 (2017)。森林中看不到的芳香維他命。台灣林業，43(6)，24-32。
守口徹 (2021)。油與脂肪的驚人真相〔林巍翰譯〕。PCuSER電腦人文化。
成癮 (2024年7月12日)。載於維基百科。https://zh.wikipedia.org/zh-tw/%E6%88%90%E7%98%BE
林怡文（2017）。芬多精成分之生心理效益初探－以α-蒎烯及芳樟醇為例〔碩士論文，國立臺灣大學〕。華藝線上圖書館。https://doi.org/10.6342%2fNTU201700454
林群雅、張上鎮、陳盈如、鄭森松（2016）。臺灣森林芬多精釋出量監測及其功效－以柳杉為例。林業研究專訊，23(3)，48-51。https://www.airitilibrary.com/Article/Detail?DocID=16056922-201606-201608240071-201608240071-48-51
紀佳汝，蔡明哲，蘇大成，郭宇修，曹崇銘 (2017)。森林環境中空氣負離子濃度研究之文獻探討。中華林學季刊，50 (2) ， 103 – 116。
徐再靜，曾博修 (2020年12月13日)。腸道菌研究成為最夯趨勢:在注意力不足過動症中扮演重要角色的證據。https://www.mentalwe.com/focus/00021/
啟端編輯 (2021年8月4日)。 牛奶、乳製品對孩子有害嗎？https://www.blog-kickstart.com/archives/4335
康健嚴選 (2021年10月14日)。營養師推薦100%無添加，原豆原脂純黑巧克力，保留原營養價值。康健雜誌。https://reurl.cc/LWoKrx
張立人 (2021)。大腦營養學全書。商週出版。
許美雅 (2024年5月1日)。長庚醫訊：善用飲食幫助睡眠。https://www.cgmh.org.tw/cgmn/category.asp?id_seq=0903020
陳智光 (2014年8月1)。長庚醫訊：談輔助及另類醫療在現代醫學之角色。https://www.cgmh.org.tw/cgmn/category.asp?id_seq=1407001
陳慶源、黃崇真、邱雪惠、廖啟成（2007）。乳酸菌之保健功效與產品開發。農業生技產業季刊，(11)，60-68。https://doi.org/10.29657/ABIQ.200710.0010
鈕文英 (2019)。質性研究方法與論文寫作二版。雙葉書廊。
雲林縣衛生局食品衛生科 (2019年11月25日)。小心隱形的油脂殺手-反式脂肪！https://ylshb.yunlin.gov.tw/News_Content.aspx?n=5227&s=269981
黃惠姍 (2017年2月13日)。 吃黑巧克力抗氧化、心情好！4種人不適合https://www.commonhealth.com.tw/article/74175
黃馨儀， 王瑞霞 (2016)。影響學齡前兒童父母高熱量飲食餵養行為因素之探討－計畫行為理論之應用。長庚護理，27 (2)，167-179。
農業部林業及自然保育署臺東分署 (2016年8月6日)。柳杉 (Cryptomeria japonica)。https://taitung.forest.gov.tw/0000132
蔡岳君 (2023年4月6)。溫度與失眠的關係，你睡不好，說不定是溫度惹的禍！好眠事務所。https://reurl.cc/3XMpN0
蔣華玉，王永剛 (2016)。神经元放射状迁移分子的研究进展。同 济 大 学 学 报 ( 医 学 版 )，37 ( 1)，124-128。
鄭景鵬、衛強、曹崇銘（2020）。溪頭森林環境空氣中負離子濃度的季節變動研究。國立臺灣大學生物資源暨農學院實驗林研究報告，34 (1)，67-78。https://doi.org/10.6542/EFNTU.202003_34(1).0006
鄭晴予(2022年10月27日) 除了供應大腸細胞能量，還能抑制大腸癌，如何確保體內有足夠的「短鏈脂肪酸」。https://www.thenewslens.com/article/175162
鮑冠吟、林思瑜、林玲伊（2014）。自閉症類群障礙症兒童的感覺處理問題：文獻回顧。臺灣職能治療研究與實務雜誌，10 (2)，103-114。https://doi.org/10.6534/jtotrp.2014.10(2).103
二、 英文部分
Abbasi, K., Foshati, S., Mehrabani, S., Ghiasvand, R., Bagherniya, M., & Rouhani, M. H.. (2022). Diet cost plays a key role in determining the risk of pediatric attention deficit hyperactivity disorder: Findings from a case–control study. Food Science & Nutrition, 10(12), 4339–4344. https://doi.org/10.1002/fsn3.3026
Agostoni, C., Nobile, M., Ciappolino, V., Delvecchio, G., Tesei, A., Turolo, S., Crippa, A., Mazzocchi, A., Altamura, C. A., & Brambilla, P. (2017). The role of omega-3 fatty acids in developmental psychopathology: a systematic review on early psychosis, autism, and ADHD. International journal of molecular sciences, 18(12), 2608. https://doi.org/10.3390/ijms18122608
Altun, H., Kurutaş, E. B., Şahin, N., Güngör, O., & Fındıklı, E. (2018). The levels of vitamin D, vitamin D receptor, homocysteine and complex B vitamin in children with autism spectrum disorders. Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology, 16(4), 383–390. https://doi.org/10.9758/cpn.2018.16.4.383
Baker, E. K., & Richdale, A. L. (2017). Examining the behavioural sleep- wake rhythm in adults with autism spectrum disorder and no comorbid intellectual disability. Journal of autism and developmental disorders, 47(4), 1207–1222. https://doi.org/10.1007/s10803-017-3042-3
Bandini, L. G., Anderson, S. E., Curtin, C., Cermak, S., Evans, E. W., Scampini, R., Maslin, M., & Must, A. (2010). Food selectivity in children with autism spectrum disorders and typically developing children. The Journal of pediatrics, 157(2), 259–264. https://doi.org/10.1016/j.jpeds.2010.02.013
Becker, S. P., Tamm, L., Epstein, J. N., & Beebe, D. W. (2020). Impact of sleep restriction on affective functioning in adolescents with attention-deficit/hyperactivity disorder. Journal of child psychology and psychiatry, and allied disciplines, 61(10), 1160–1168. https://doi.org/10.1111/jcpp.13235
Ben-Sasson, A., Cermak, S. A., Orsmond, G. I., Tager-Flusberg, H., Kadlec, M. B., & Carter, A. S. (2008). Sensory clusters of toddlers with autism spectrum disorders: differences in affective symptoms. Journal of Child Psychology and Psychiatry, 49(8), 817-825. https://doi.org/10.1111/j.1469-7610.2008.01899.x
Bos, D. J., Oranje, B., Veerhoek, E. S., Van Diepen, R. M., Weusten, J. M., Demmelmair, H., Koletzko, B., de Sain-van der Velden, M. G., Eilander, A., Hoeksma, M., & Durston, S. (2015). Reduced symptoms of inattention after dietary omega-3 fatty acid supplementation in boys with and without attention deficit/ hyperactivity disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 40(10), 2298–2306. https://doi.org/10.1038/npp.2015.73
Buie T. (2013). The relationship of autism and gluten. Clinical therapeutics, 35(5), 578–583. https://doi.org/10.1016/j.clinthera.2013.04.011
Buie, T., Campbell, D. B., Fuchs, G. J., 3rd, Furuta, G. T., Levy, J., Vandewater, J., Whitaker, A. H., Atkins, D., Bauman, M. L., Beaudet, A. L., Carr, E. G., Gershon, M. D., Hyman, S. L., Jirapinyo, P., Jyonouchi, H., Kooros, K., Kushak, R., Levitt, P., Levy, S. E., Lewis, J. D., … Winter, H. (2010). Evaluation, Diagnosis, and Treatment of Gastrointestinal Disorders in Individuals With ASDs: A Consensus Report. Pediatrics, 125,( Suppl 1), S1–S18. https://doi.org/10.1542/peds.2009-1878C
Cash, S. S., Halgren, E., Dehghani, N., Rossetti, A. O., Thesen, T., Wang, C., Devinsky, O., Kuzniecky, R., Doyle, W., Madsen, J. R., Bromfield, E., Eross, L., Halász, P., Karmos, G., Csercsa, R., Wittner, L., & Ulbert, I. (2009). The human K-complex represents an isolated cortical down-state. Science (New York, N.Y.), 324(5930), 1084–1087. https://doi.org/10.1126/science.1169626
Chen, C., Nakagawa, S., An, Y., Ito, K., Kitaichi, Y., & Kusumi, I. (2017). The exercise-glucocorticoid paradox: hHow exercise is beneficial to cognition, mood, and the brain while increasing glucocorticoid levels. Frontiers in neuroendocrinology, 44, 83–102. https://doi.org/10.1016/j.yfrne.2016.12.001
Chen, L., Shi, X. J., Liu, H., Mao, X., Gui, L. N., Wang, H., & Cheng, Y. (2021). Oxidative stress marker aberrations in children with autism spectrum disorder: a systematic review and meta-analysis of 87 studies (N = 9109). Translational psychiatry, 11(1), 15. https://doi.org/10.1038/s41398-020-01135-3
Chun, M. H., Chang, M. C., & Lee, S. J. (2017). The effects of forest therapy on depression and anxiety in patients with chronic stroke. The International journal of neuroscience, 127(3), 199–203. https://doi.org/10.3109/00207454.2016.1170015
Chun, M. H., Chang, M. C., & Lee, S. J. (2017). The effects of forest therapy on depression and anxiety in patients with chronic stroke. The International journal of neuroscience, 127(3), 199–203. https://doi.org/10.3109/00207454.2016.1170015
Cohen, S., Conduit, R., Lockley, S. W., Rajaratnam, S. M., & Cornish, K. M. (2014). The relationship between sleep and behavior in autism spectrum disorder (ASD): a review. Journal of neurodevelopmental disorders, 6(1), 44. https://doi.org/10.1186/1866-1955-6-44
Crichton, G. E., Elias, M. F., & Alkerwi, A. (2016). Chocolate intake is associated with better cognitive function: The Maine-Syracuse Longitudinal Study. Appetite, 100, 126–132. https://doi.org/10.1016/j.appet.2016.02.010
Curtin, C., Anderson, S. E., Must, A., & Bandini, L. (2010). The prevalence of obesity in children with autism: a secondary data analysis using nationally representative data from the National Survey of Children's Health. BMC pediatrics, 10, 11. https://doi.org/10.1186/1471-2431-10-11
Daniel A. Rossignol, J. Jeffrey Bradstreet. Evidence of mitochondrial dysfunction in autism and implications for treatment. American Journal of Biochemistry and Biotechnology 4 (2): 208-217
Dayawansa, S., Umeno, K., Takakura, H., Hori, E., Tabuchi, E., Nagashima, Y., Oosu, H., Yada, Y., Suzuki, T., Ono, T., & Nishijo, H. (2003). Autonomic responses during inhalation of natural fragrance of Cedrol in humans. Autonomic neuroscience : basic & clinical, 108(1-2), 79–86. https://doi.org/10.1016/j.autneu.2003.08.002
Del-Ponte, B., Anselmi, L., Assunção, M. C. F., Tovo-Rodrigues, L., Munhoz, T. N., Matijasevich, A., Rohde, L. A., & Santos, I. S. (2019). Sugar consumption and attention-deficit/hyperactivity disorder (ADHD): A birth cohort study. Journal of affective disorders, 243, 290–296. https://doi.org/10.1016/j.jad.2018.09.051
Dickerson, F., Severance, E., & Yolken, R. (2017). The microbiome, immunity, and schizophrenia and bipolar disorder. Brain, behavior, and immunity, 62, 46–52. https://doi.org/10.1016/j.bbi.2016.12.010
Doenyas C. (2018). Dietary interventions for autism spectrum disorder: nNew perspectives from the gut-brain axis. Physiology & behavior, 194, 577–582. https://doi.org/10.1016/j.physbeh.2018.07.014
Fultz, N. E., Bonmassar, G., Setsompop, K., Stickgold, R. A., Rosen, B. R., Polimeni, J. R., & Lewis, L. D. (2019). Coupled electrophysiological, hemodynamic, and cerebrospinal fluid oscillations in human sleep. Science (New York, N.Y.), 366(6465), 628–631. https://doi.org/10.1126/science.aax5440
Furuyashiki, A., Tabuchi, K., Norikoshi, K., Kobayashi, T., & Oriyama, S. (2019). A comparative study of the physiological and psychological effects of forest bathing (Shinrin-yoku) on working age people with and without depressive tendencies. Environmental health and preventive medicine, 24(1), 46. https://doi.org/10.1186/s12199-019-0800-1
Ghanizadeh A. (2013). A systematic review of magnesium therapy for treating attention deficit hyperactivity disorder. Archives of Iranian medicine, 16(7), 412–417.
Ghanizadeh, A., Akhondzadeh, S., Hormozi, M., Makarem, A., Abotorabi-Zarchi, M., & Firoozabadi, A. (2012). Glutathione-related factors and oxidative stress in autism, a review. Current medicinal chemistry, 19(23), 4000–4005. https://doi.org/10.2174/092986712802002572
Gillies, D., Leach, M. J., & Perez Algorta, G. (2023). Polyunsaturated fatty acids (PUFA) for attention deficit hyperactivity disorder (ADHD) in children and adolescents. The Cochrane database of systematic reviews, 4(4), CD007986. https://doi.org/10.1002/14651858.CD007986.pub3
Groves, N. J., McGrath, J. J., & Burne, T. H. (2014). Vitamin D as a neurosteroid affecting the developing and adult brain. Annual review of nutrition, 34, 117–141. https://doi.org/10.1146/annurev-nutr-071813-105557
Han, J. W., Choi, H., Jeon, Y. H., Yoon, C. H., Woo, J. M., & Kim, W. (2016). The effects of forest therapy on coping with chronic widespread pain: Physiological and psychological differences between participants in a forest therapy program and a control group. International journal of environmental research and public health, 13(3), 255. https://doi.org/10.3390/ijerph13030255
Hansen, M. M., Jones, R., & Tocchini, K. (2017). Shinrin-Yoku (forest bathing) and nature therapy: A state-of-the- art review. International journal of environmental research and public health, 14(8), 851. https://doi.org/10.3390/ijerph14080851
Howard Chiu, Sila Genc, Charles B. Malpas, Emma Sciberras, Jan M. Nicholson, Daryl Efron, Timothy J. Silk. (2021). Prefrontal and frontostriatal structures mediate academic outcomes associated with ADHD symptoms. Brain Disorders 4(12):100023, https://doi.org/10.1016/j.dscb.2021.100023
Huang, C. L., Wang, J. J., & Ho, C. H. (2020). Trends in incidence rates of diagnosed attention-deficit/hyperactivity disorder (ADHD) over 12 years in Taiwan: A nationwide population-based study. Psychiatry research, 284, 112792. https://doi.org/10.1016/j.psychres.2020.112792
Hvolby A. (2015). Associations of sleep disturbance with ADHD: implications for treatment. Attention deficit and hyperactivity disorders, 7(1), 1–18. https://doi.org/10.1007/s12402-014-0151-0
Igarashi, M., Song, C., Ikei, H., & Miyazaki, Y.. (2015). Effect of Stimulation by Foliage Plant Display Images on Prefrontal Cortex Activity: A Comparison with Stimulation using Actual Foliage Plants. Journal of Neuroimaging, 25(1), 127–130. https://doi.org/10.1111/jon.12078
Jafari Mohammadabadi, H., Rahmatian, A., Sayehmiri, F., & Rafiei, M. (2020). The Relationship Between the Level of Copper, Lead, Mercury and Autism Disorders: A Meta-Analysis. Pediatric Health, Medicine and Therapeutics, Volume 11, 369–378. https://doi.org/10.2147/phmt.s210042
Jo, H., Rodiek, S., Fujii, E., Miyazaki, Y., Park, B.-J., & Ann, S.-W.. (2013). Physiological and Psychological Response to Floral Scent. Hortscience, 48(1), 82–88. https://doi.org/10.21273/hortsci.48.1.82
Jones, T. W., Borg, W. P., Boulware, S. D., McCarthy, G., Sherwin, R. S., & Tamborlane, W. V. (1995). Enhanced adrenomedullary response and increased susceptibility to neuroglycopenia: Mechanisms underlying the adverse effects of sugar ingestion in healthy children. The Journal of Pediatrics, 126(2), 171-177. https://doi.org/10.1016/S0022-3476(95)70541-4
Kerzner, B., Milano, K., MacLean, W. C., Jr, Berall, G., Stuart, S., & Chatoor, I. (2015). A practical approach to classifying and managing feeding difficulties. Pediatrics, 135(2), 344–353. https://doi.org/10.1542/peds.2014-1630
Kirov, R., Kinkelbur, J., Banaschewski, T., & Rothenberger, A. (2007). Sleep patterns in children with attention-deficit/hyperactivity disorder, tic disorder, and comorbidity. Journal of child psychology and psychiatry, and allied disciplines, 48(6), 561–570. https://doi.org/10.1111/j.1469-7610.2007.01729.x
Knight, R. M., & Johnson, C. M. (2014). Using a Behavioral Treatment Package for Sleep Problems in Children With Autism Spectrum Disorders. Child & Family Behavior Therapy, 36(3), 204–221. https://doi.org/10.1080/07317107.2014.934171
Kotera, Y., Richardson, M., & Sheffield, D.. (2022). Effects of Shinrin-Yoku (Forest Bathing) and Nature Therapy on Mental Health: a Systematic Review and Meta-analysis. International Journal of Mental Health and Addiction, 20(1), 337–361. https://doi.org/10.1007/s11469-020-00363-4
Kral, T. V., Souders, M. C., Tompkins, V. H., Remiker, A. M., Eriksen, W. T., & Pinto-Martin, J. A. (2015). Child eating behaviors and caregiver feeding practices in children with autism spectrum disorders. Public health nursing (Boston, Mass.), 32(5), 488–497. https://doi.org/10.1111/phn.12146
Kurdziel, L., Duclos, K., & Spencer, R. M. (2013). Sleep spindles in midday naps enhance learning in preschool children. Proceedings of the National Academy of Sciences of the United States of America, 110(43), 17267–17272. https://doi.org/10.1073/pnas.1306418110
Leader, G., Dooley, E., Whelan, S., Gilroy, S. P., Chen, J. L., Farren Barton, A., Coyne, R., & Mannion, A. (2022). Attention-deficit/ hyperactivity disorder symptoms, gastrointestinal symptoms, sleep problems, challenging behavior, adaptive behavior, and quality of life in children and adolescents with autism spectrum disorder. Developmental neurorehabilitation, 25(4), 217–228. https://doi.org/10.1080/17518423.2021.1964005.
Lewis L. D. (2021). The interconnected causes and consequences of sleep in the brain. Science (New York, N.Y.), 374(6567), 564–568. https://doi.org/10.1126/science.abi8375
Li, Q., Morimoto, K., Kobayashi, M., Inagaki, H., Katsumata, M., Hirata, Y., Hirata, K., Suzuki, H., Li, Y. J., Wakayama, Y., Kawada, T., Park, B. J., Ohira, T., Matsui, N., Kagawa, T., Miyazaki, Y., & Krensky, A. M. (2008). Visiting a forest, but not a city, increases human natural killer activity and expression of anti-cancer proteins. International journal of immunopathology and pharmacology, 21(1), 117–127. https://doi.org/10.1177/039463200802100113
Lima, P. A., Sampaio, L. P., & Damasceno, N. R. (2014). Neurobiochemical mechanisms of a ketogenic diet in refractory epilepsy. Clinics (Sao Paulo, Brazil), 69(10), 699–705. https://doi.org/10.6061/clinics/2014(10)09
Liu, W. H., Chuang, H. L., Huang, Y. T., Wu, C. C., Chou, G. T., Wang, S., & Tsai, Y. C. (2016). Alteration of behavior and monoamine levels attributable to Lactobacillus plantarum PS128 in germ-free mice. Behavioural Brain Research, 298(Pt B), 202–209. https://doi.org/10.1016/j.bbr.2015.10.046
Loe, I. M., & Feldman, H. M. (2007). Academic and educational outcomes of children with ADHD. Ambulatory pediatrics : the official journal of the Ambulatory Pediatric Association, 7(1 Suppl), 82–90. https://doi.org/10.1016/j.ambp.2006.05.005
Lok, K. Y., Chan, R. S., Lee, V. W., Leung, P. W., Leung, C., Leung, J., & Woo, J. (2013). Food additives and behavior in 8- to 9-year-old children in Hong Kong: a randomized, double-blind, placebo-controlled trial. Journal of Developmental & Behavioral PediatricsJournal of developmental and behavioral pediatrics : JDBP, 34(9), 642–650. https://doi.org/10.1097/DBP.0000000000000005
Louveau, A., Smirnov, I., Keyes, T. J., Eccles, J. D., Rouhani, S. J., Peske, J. D., Derecki, N. C., Castle, D., Mandell, J. W., Lee, K. S., Harris, T. H., & Kipnis, J.. (2015). Structural and functional features of central nervous system lymphatic vessels. Nature, 523(7560), 337–341. https://doi.org/10.1038/nature14432
Manivasagam, T., Arunadevi, S., Essa, M. M., SaravanaBabu, C., Borah, A., Thenmozhi, A. J., & Qoronfleh, M. W. (2020). Role of oxidative stress and antioxidants in autism. Advances in neurobiology, 24, 193–206. https://doi.org/10.1007/978-3-030-30402-7_7
Mao, G. X., Cao, Y. B., Lan, X. G., He, Z. H., Chen, Z. M., Wang, Y. Z., Hu, X. L., Lv, Y. D., Wang, G. F., & Yan, J. (2012). Therapeutic effect of forest bathing on human hypertension in the elderly. Journal of cardiology, 60(6), 495–502. https://doi.org/10.1016/j.jjcc.2012.08.003
Martinat, M., Rossitto, M., Di Miceli, M., & Layé, S. (2021). Perinatal dietary polyunsaturated fatty acids in brain development, role in neurodevelopmental disorders. Nutrients, 13(4), 1185. https://doi.org/10.3390/nu13041185
Martinez-Cayuelas, E., Gavela-Pérez, T., Rodrigo-Moreno, M., Losada-Del Pozo, R., Moreno-Vinues, B., Garces, C., & Soriano-Guillén, L.. (2024). Sleep Problems, Circadian Rhythms, and Their Relation to Behavioral Difficulties in Children and Adolescents with Autism Spectrum Disorder. Journal of Autism and Developmental Disorders, 54(5), 1712–1726. https://doi.org/10.1007/s10803-023-05934-7
Matson, J. L., Wilkins, J., & Ancona, M. (2008). Autism in adults with severe intellectual disability: An empirical study of symptom presentation. Journal of Intellectual & Developmental Disability, 33(1), 36–42. https://doi.org/10.1080/13668250701829837
Mazurek, M. O., Dovgan, K., Neumeyer, A. M., & Malow, B. A. (2019). Course and predictors of sleep and co-occurring problems in children with autism spectrum disorder. Journal of autism and developmental disorders, 49(5), 2101–2115. https://doi.org/10.1007/s10803-019-03894-5
McCaffrey, R., Hanson, C., & McCaffrey, W. (2010). Garden walking for depression: a A research report. Holistic nursing practice, 24(5), 252–259. https://doi.org/10.1097/HNP.0b013e3181f1acd7
McCann, D., Barrett, A., Cooper, A., Crumpler, D., Dalen, L., Grimshaw, K., Kitchin, E., Lok, K., Porteous, L., Prince, E., Sonuga-Barke, E., Warner, J. O., & Stevenson, J. (2007). Food additives and hyperactive behaviour in 3-year-old and 8/9-year-old children in the community: a randomised, double-blinded, placebo-controlled trial. The Lancet (London, England), 370(9598), 1560–1567. https://doi.org/10.1016/S0140-6736(07)61306-3
McGuinness, G., & Kim, Y. (2020). Sulforaphane treatment for autism spectrum disorder: a systematic review. EXCLI jJournal, 19, 892–903. https://doi.org/10.17179/excli2020-2487
Mehrazad‐Saber, Z., Kheirouri, S., & Noorazar, S.. (2018). Effects of l‐Carnosine Supplementation on Sleep Disorders and Disease Severity in Autistic Children: A Randomized, Controlled Clinical Trial. Basic & Clinical Pharmacology & Toxicology, 123(1), 72–77. https://doi.org/10.1111/bcpt.12979
Mehta, R., Bhattacharya, R., & Mallick, B. N.. (2022). Sleep and Neuroimmunomodulation for Maintenance of Optimum Brain Function: Role of Noradrenaline. Brain Sciences, 12(12), 1725. https://doi.org/10.3390/brainsci12121725
Mensi, M. M., Rogantini, C., Marchesi, M., Borgatti, R., & Chiappedi, M.. (2021). Lactobacillus plantarum PS128 and Other Probiotics in Children and Adolescents with Autism Spectrum Disorder: A Real-World Experience. Nutrients, 13(6), 2036. https://doi.org/10.3390/nu13062036
Montgomery, P., Burton, J. R., Sewell, R. P., Spreckelsen, T. F., & Richardson, A. J.. (2013). Low Blood Long Chain Omega-3 Fatty Acids in UK Children Are Associated with Poor Cognitive Performance and Behavior: A Cross-Sectional Analysis from the DOLAB Study. PLOS ONE, 8(6), e66697. https://doi.org/10.1371/journal.pone.0066697
Mou, Y., Blok, E., Barroso, M., Jansen, P. W., White, T., & Voortman, T. (2023). Dietary patterns, brain morphology and cognitive performance in children: Results results from a prospective population-based study. European journal of epidemiology, 38(6), 669–687. https://doi.org/10.1007/s10654-023-01012-5
Mousain-Bosc, M., Roche, M., Polge, A., Pradal-Prat, D., Rapin, J., & Bali, J. P. (2006). Improvement of neurobehavioral disorders in children supplemented with magnesium-vitamin B6. I. Attention deficit hyperactivity disorders. Magnesium research, 19(1), 46–52.
Mustafa H. Gandhi, Prabhu D. Emmady. (2023). Physiology, K Complexcomplex. NCBI. https://www.ncbi.nlm.nih.gov/books/NBK557469/
Nye, C., & Brice, A. (2005). Combined vitamin B6-magnesium treatment in autism spectrum disorder. Cochrane Database of Systematic Reviews. https://doi.org/10.1002/14651858.cd003497.pub2
Olimpia Pino, Francesco La Ragione. (2013). There’s Something in the Air: Empirical Evidence for the Effects of Negative Air Ions (NAI) on Psychophysiological State and Performance. Research in Psychology and Behavioral Sciences, 1(4), 48-53. DOI:10.12691/rpbs-1 -4
Pannaraj, P. S., Li, F., Cerini, C., Bender, J. M., Yang, S., Rollie, A., Adisetiyo, H., Zabih, S., Lincez, P. J., Bittinger, K., Bailey, A., Bushman, F. D., Sleasman, J. W., & Aldrovandi, G. M. (2017). Association between breast milk bacterial communities and establishment and development of the infant gut microbiome. JAMA pediatrics, 171(7), 647–654. https://doi.org/10.1001/jamapediatrics.2017.0378
Park, S., Cho, S. C., Cho, I. H., Kim, B. N., Kim, J. W., Shin, M. S., Chung, U. S., Park, T. W., Son, J. W., & Yoo, H. J. (2012). Sleep problems and their correlates and comorbid psychopathology of children with autism spectrum disorders. Research in Autism Spectrum Disorders, 6(3), 1068-1072. https://doi.org/10.1016/j.rasd.2012.02.004
Patrick, R. P., & Ames, B. N. (2015). Vitamin D and the omega-3 fatty acids control serotonin synthesis and action, part 2: relevance for ADHD, bipolar disorder, schizophrenia, and impulsive behavior. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(6), 2207–2222. https://doi.org/10.1096/fj.14-268342
Robinette, L. M., Hatsu, I. E., Johnstone, J. M., Tost, G., Bruton, A. M., Leung, B. M. Y., Odei, J. B., Orchard, T., Gracious, B. L., & Arnold, L. E. (2023). Fruit and vegetable intake is inversely associated with severity of inattention in a pediatric population with ADHD symptoms: the MADDY Study. Nutritional neuroscience, 26(6), 572–581. https://doi.org/10.1080/1028415X.2022.2071805
Rose, S., Melnyk, S., Pavliv, O., Bai, S., Nick, T. G., Frye, R. E., & James, S. J. (2012). Evidence of oxidative damage and inflammation associated with low glutathione redox status in the autism brain. Translational psychiatry, 2(7), e134. https://doi.org/10.1038/tp.2012.61
Rossignol, D. A. & Bradstreet, J. J. (2008). Evidence of mitochondrial dysfunction in autism and implications for treatment. American Journal of Biochemistry and Biotechnology, 4(2), 208-217. https://doi.org/10.3844/ajbbsp.2008.208.217
Roumen Kirov, Joerg Kinkelbur, Tobias Banaschewski, Aribert Rothenberger. (2007). Sleep patterns in children with attention-deficit/hyperactivity disorder, tic disorder, and comorbidity. Child and Adolescent Psychiatry. https://doi.org/10.1111/j.1469-7610.2007.01729.x
Sadek, A., Berk, L. S., Mainess, K., & Daher, N. S. (2018). A Pilot Study: Parent Perceptions of Behavior Change in Their Child With Autism Spectrum Disorder Following High Antioxidant Cacao Consumption. Integrative medicine (Encinitas, Calif.), 17(5), 31–38.
Seiverling, L., Williams, K., & Sturmey, P.. (2010). Assessment of feeding problems in children with autism spectrum disorders. Journal of Developmental and Physical Disabilities, 22(4), 401–413. https://doi.org/10.1007/s10882-010-9206-0
Sharon, G., Cruz, N. J., Kang, D. W., Gandal, M. J., Wang, B., Kim, Y. M., Zink, E. M., Casey, C. P., Taylor, B. C., Lane, C. J., Bramer, L. M., Isern, N. G., Hoyt, D. W., Noecker, C., Sweredoski, M. J., Moradian, A., Borenstein, E., Jansson, J. K., Knight, R., Metz, T. O., … Mazmanian, S. K. (2019). Human gut microbiota from autism spectrum disorder promote behavioral symptoms in mice. Cell, 177(6), 1600–1618.e17. https://doi.org/10.1016/j.cell.2019.05.004
Shibagaki, M., Kiyono, S., & Watanabe, K.. (1982). Spindle Evolution in Normal and Mentally Retarded Children: A Review. SLEEP, 5(1), 47–57. https://doi.org/10.1093/sleep/5.1.47
Slutsky, I., Abumaria, N., Wu, L. J., Huang, C., Zhang, L., Li, B., Zhao, X., Govindarajan, A., Zhao, M. G., Zhuo, M., Tonegawa, S., & Liu, G. (2010). Enhancement of learning and memory by elevating brain magnesium. Neuron, 65(2), 165–177. https://doi.org/10.1016/j.neuron.2009.12.026
Song, C., Ikei, H., & Miyazaki, Y.. (2016). Physiological Effects of Nature Therapy: A Review of the Research in Japan. International Journal of Environmental Research and Public Health, 13(8), 781. https://doi.org/10.3390/ijerph13080781
Song, C., Ikei, H., Kobayashi, M., Miura, T., Taue, M., Kagawa, T., Li, Q., Kumeda, S., Imai, M., & Miyazaki, Y.. (2015). Effect of Forest Walking on Autonomic Nervous System Activity in Middle-Aged Hypertensive Individuals: A Pilot Study. International Journal of Environmental Research and Public Health, 12(3), 2687–2699. https://doi.org/10.3390/ijerph120302687
Stirone, C., Duckles, S. P., Krause, D. N., & Procaccio, V. (2005). Estrogen increases mitochondrial efficiency and reduces oxidative stress in cerebral blood vessels. Molecular pharmacology, 68(4), 959–965. https://doi.org/10.1124/mol.105.014662
Sun, C., Zou, M., Wang, X., Xia, W., Ma, Y., Liang, S., Hao, Y., Wu, L., & Fu, S. (2018). FADS1-FADS2 and ELOVL2 gene polymorphisms in susceptibility to autism spectrum disorders in Chinese children. BMC psychiatry, 18(1), 283. https://doi.org/10.1186/s12888-018-1868-7
Sun, L., Ye, K. X., Wong, H. L. K., Wang, L., Lim, S. L., Chao, Y. X., Zhang, C., Yap, K. Z., & Feng, L.. (2023). The Effects of Medium Chain Triglyceride for Alzheimer’s Disease Related Cognitive Impairment: A Systematic Review and Meta-Analysis. Journal of Alzheimer's Disease, 94(2), 441–456. https://doi.org/10.3233/jad-230406
Suzuki, K., Sugihara, G., Ouchi, Y., Nakamura, K., Futatsubashi, M., Takebayashi, K., Yoshihara, Y., Omata, K., Matsumoto, K., Tsuchiya, K. J., Iwata, Y., Tsujii, M., Sugiyama, T., & Mori, N. (2013). Microglial activation in young adults with autism spectrum disorder. JAMA psychiatry, 70(1), 49–58. https://doi.org/10.1001/jamapsychiatry.2013.272
Tataru, C., Martin, A., Dunlap, K., Peras, M., Chrisman, B. S., Rutherford, E., Deitzler, G. E., Phillips, A., Yin, X., Sabino, K., Hannibal, R. L., Hartono, W., Lin, M., Raack, E., Wu, Y., DeSantis, T. Z., Iwai, S., Wall, D. P., & David, M. M. (2021). Longitudinal study of stool-associated microbial taxa in sibling pairs with and without autism spectrum disorder. ISME communications, 1(1), 80. https://doi.org/10.1038/s43705-021-00080-6
Tsao, T. M., Tsai, M. J., Hwang, J. S., Cheng, W. F., Wu, C. F., Chou, C. K., & Su, T. C. (2018). Health effects of a forest environment on natural killer cells in humans: an observational pilot study. Oncotarget, 9(23), 16501–16511. https://doi.org/10.18632/oncotarget.24741
Tsujiguchi, H., Miyagi, S., Nguyen, T. T. T., Hara, A., Ono, Y., Kambayashi, Y., Shimizu, Y., Nakamura, H., Suzuki, K., Suzuki, F., & Nakamura, H.. (2020). Relationship between Autistic Traits and Nutrient Intake among Japanese Children and Adolescents. Nutrients, 12(8), 2258. https://doi.org/10.3390/nu12082258
Tsunetsugu, Y., Park, B. J., & Miyazaki, Y. (2010). Trends in research related to "Shinrin-yoku" (taking in the forest atmosphere or forest bathing) in Japan. Environmental health and preventive medicine, 15(1), 27–37. https://doi.org/10.1007/s12199-009-0091-z
Tudor, M. E., Hoffman, C. D., & Sweeney, D. P. (2012). Children With Autism: Sleep Problems and Symptom Severity. Focus on Autism and Other Developmental Disabilities, 27(4), 254-262. https://doi.org/10.1177/1088357612457989
Van Cauter, E., & Plat, L. (1996). Physiology of growth hormone secretion during sleep. The Journal of pediatrics, 128(5 Pt 2), S32–S37. https://doi.org/10.1016/s0022-3476(96)70008-2
van Dijk, M. W. G., Buruma, M. E., & Blijd-Hoogewys, E. M. A. (2021). Detecting feeding problems in young children with autism spectrum disorder. Journal of autism and developmental disorders, 51(11), 4115–4127. https://doi.org/10.1007/s10803-021-04869-1
van Elst, K., Brouwers, J. F., Merkens, J. E., Broekhoven, M. H., Birtoli, B., Helms, J. B., & Kas, M. J. H. (2019). Chronic dietary changes in n-6/n-3 polyunsaturated fatty acid ratios cause developmental delay and reduce social interest in mice. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 29(1), 16–31. https://doi.org/10.1016/j.euroneuro.2018.11.1106
Verlaet, A. A. J., Breynaert, A., Ceulemans, B., De Bruyne, T., Fransen, E., Pieters, L., Savelkoul, H. F. J., & Hermans, N. (2019). Oxidative stress and immune aberrancies in attention-deficit/hyperactivity disorder (ADHD): a case-control comparison. European child & adolescent psychiatry, 28(5), 719–729. https://doi.org/10.1007/s00787-018-1239-4
Verlaet, A. A. J., Maasakkers, C. M., Hermans, N., & Savelkoul, H. F. J. (2018). Rationale for Dietary dietary Antioxidant antioxidant Treatment treatment of ADHD. Nutrients, 10(4), 405. https://doi.org/10.3390/nu10040405
Viktorinova, A., Ursinyova, M., Trebaticka, J., Uhnakova, I., Durackova, Z., & Masanova, V. (2016). Changed plasma levels of zinc and copper to zinc ratio and their possible associations with parent- and teacher- rated symptoms in children with attention- deficit hyperactivity disorder. Biological trace element research, 169(1), 1–7. https://doi.org/10.1007/s12011-015-0395-3
Vissoker, R. E., Latzer, Y., & Gal, E.. (2015). Eating and feeding problems and gastrointestinal dysfunction in Autism Spectrum Disorders. Research in Autism Spectrum Disorders, 12, 10–21. https://doi.org/10.1016/j.rasd.2014.12.010
Wei-Hsien Liu, Hsiao-Li Chuang, Yen-Te Huang, Chien-Chen Wu, Geng-Ting Chou, Sabrina Wang, Ying-Chieh Tsai. (2016). Alteration of behavior and monoamine levels attributable to Lactobacillus plantarum PS128 in germ-free mice. Behavioural Brain Research, 298, Part B, 202-209, https://doi.org/10.1016/j.bbr.2015.10.046
Whiteley, P.. (2017). Food and the gut: relevance to some of the autisms. Proceedings of the Nutrition Society, 76(4), 478–483. https://doi.org/10.1017/s0029665117002798
Wolraich, M. L., Wilson, D. B., & White, J. W. (1995). The effect of sugar on behavior or cognition in children.: A meta-analysis. JAMA, 274(20), 1617–1621. https://doi.org/10.1001/jama.1995.03530200053037
Yang, H., & Wu, X. (2020). The Correlation Between Vitamin D Receptor (VDR) Gene Polymorphisms and Autism: A Meta-analysis. Journal of molecular neuroscience : MN, 70(2), 260–268. https://doi.org/10.1007/s12031-019-01464-z
Yost, T. J., Erskine, J. M., Gregg, T. S., Podlecki, D. L., Brass, E. P., & Eckel, R. H. (1994). Dietary substitution of medium chain triglycerides in subjects with non-insulin-dependent diabetes mellitus in an ambulatory setting: impact on glycemic control and insulin-mediated glucose metabolism. Journal of the American College of Nutrition, 13(6), 615–622. https://doi.org/10.1080/07315724.1994.10718457
Yost, T. J., Erskine, J. M., Gregg, T. S., Podlecki, D. L., Brass, E. P., & Eckel, R. H. (1994). Dietary substitution of medium chain triglycerides in subjects with non-insulin-dependent diabetes mellitus in an ambulatory setting: impact on glycemic control and insulin-mediated glucose metabolism. Journal of the American College of Nutrition, 13(6), 615–622. https://doi.org/10.1080/07315724.1994.10718457
Yu, H., Zhang, Z., Liu, J., Hu, P., & Liu, Z. (2020). Association study between genetic variants in vitamin D metabolism related genes and childhood autism spectrum disorder. Metabolic brain disease, 35(6), 971–978. https://doi.org/10.1007/s11011-020-00570-x