氫化反應之過程中，由於氫氣在有機溶液中之溶解度不高，反應速率往往受制於氣液介面間之質傳阻力。此外在使用多孔性觸媒時，觸媒內部之擴散阻力也會對反應速率造成限制，若處理具高黏度液體，則質傳阻力之影響將更增加。因此傳統上在氫化反應製程中，常利用滴流反應器（Trickle-Bed Reactor）增加介面質傳速率以獲得高反應量。然而受制於氫氣溶解度，也只能藉由增加壓力以增加液相中氫氣濃度，或增加反應物之停滯時間，以更增進反應器之效能。
為更能有效提升反應速率，本研究就不同之操作方式針對四氫□(Tetralin)之氫化反應進行探討，其中反應之主要產物為順式十氫□(cis-Decalin)。實驗在一填充0.5 wt % Pt/γ-Al2O3觸媒之固定床反應器內，分別於以下三種不同之操作方式進行實驗：【操作1】氣液流動相，即傳統滴流反應器之操作；【操作2】單一超臨界流體流動相；【操作3】氣液流動相，但氣相中帶有高壓之二氧化碳。
由實驗結果得到在【操作3】時可獲得最高之cis-Decalin選擇率及產率，其原因為當液相中若存有高壓之二氧化碳時，將會使液體之體積膨脹，造成其黏度降低並使氫氣於液相中之溶解度上升，進而減少介面及觸媒內部之質傳阻力並提升反應速率。此外當液相中之質傳速率提昇時，產物將能有效離開觸媒內部活性點，減少其進一步產生異構化反應之機會，因能得到較高之cis-Decalin選擇率。
在本研究中並於Liquid-Full操作之下進行存在高壓二氧化碳時之氫化反應，分別於不同之液相流速及觸媒粒徑下反應，用以觀察固液介面及觸媒內部質傳阻力對反應速率之效應，以及存在高壓二氧化碳對於質傳阻力之影響。並在可忽略氣液介面、液固介面及觸媒內部質傳阻力之操作範圍下於改變氫氣濃度進行反應，藉以獲得此反應之反應動力式。

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