目的：旨在探討高壓氧治療對衰竭運動後疲勞恢復期生理的影響。方法：以12名健康男性為研究對象，採重複實驗設計進行四組實驗處理，分別為：控制組、運動不治療組、運動後高壓氧治療組和未運動高壓氧治療組等四組。高壓氧治療為接受單次高壓氧治療，即在2ATA 環境下，吸入100%的氧氣45分鐘，療程為90分鐘。誘發運動疲勞則以跑步機漸增式衰竭運動跑至衰竭。以單因子共變數分析來考驗高壓氧治療對衰竭運動後恢復期血液中肌酸激酶(CK)、血糖(glucose)、血氨(ammonia)、皮質醇(cortisol)、睪固酮(testosterone)、皮質醇睪固酮比值(testosterone/cortisol ratio, T/C ratio)之影響。結果：（一）高壓氧治療對衰竭運動後血液中肌酸激酶活性上昇情況有下降的趨勢，但未達顯著差異(p＞.05)。（二）高壓氧治療對衰竭運動後造成血液中血氨值上升，達顯著抑制效果(p＜.05)。（三）高壓氧治療對衰竭運動後血糖提升達顯著效果(p＜.05)。（四）高壓氧治療能有效降低衰竭運動後造成的皮質醇濃度上升(p＜.05)。（五）高壓氧治療後能抑制後血液中睪固酮濃度變化(p＜.05)。（六）高壓氧治療能提升皮質醇睪固酮比值(p＜.05)。結論：高壓氧治療能有效降低衰竭運動後血液中血氨值和皮質醇濃度、抑制血液中睪固酮濃度變化，並提升血液中血糖和皮質醇睪固酮比值，有助於衰竭運動後疲勞的恢復。因此單次高壓氧治療有助於衰竭運動後疲勞的恢復。

Introduction: The purpose of this study was to investigate the effect of recovery from fatigue after exhaustive exercise with Hyperbaric Oxygen Therapy (HBO). Method: Twelve subjects (age=17.1±0.9 yrs, height=175.3±3.5 cm, weight=65.1±6.5 kg) were recruited. This study adopted a repeated sample testing, all subjects were part of the four different groups at various stages of the investigation, which consisted of: (a) control group, (b) no HBO after exhaustive exercise, (c) HBO after exhaustive exercise, and (d) HBO without exhaustive exercise. HBO was applied on a periodical basis, inhaling 100% oxygen for 45 minutes in a 2ATA environment. The whole process took 90 minutes. To induce exercise fatigue, subjects had to run on a treadmill to enhance tiredness until they were exhausted. This study employed an analysis of covariance to test the effect of HBO on the recovery of creatine kinase, glucose, ammonia, cortisol, testosterone, and the testosterone/cortisol ratio in the blood. Results: The findings were as follows: (1) HBO can lower the activity of CK in the blood after exhaustive exercise. (2) HBO can significantly control the rise of ammonia after exhaustive exercise. (3) HBO does not immediately lower glucose after exhaustive exercise. (4) HBO can effectively lower cortisol after exhaustive exercise. (5) HBO helps increase testosterone after exhaustive exercise. (6) HBO helps increase the testosterone/cortisol ratio in the blood. Based on the findings, this study supports that HBO helps recovery from fatigue after exhaustive exercise.

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