本研究利用原子轉移自由基聚合法，合成刺激應答型高分子poly(N-isopropylacrylamide)(PNIPAM)及poly(2-(dimethylamino)ethyl methacrylate)(PDEAEMA)與碳奈米球(C60)的多段嵌段高分子，包含PNIPAM171-C60、PDMAEMA99-C60、C60-PNIPAM21-C60和C60-PDMAEMA67-C60。除了以凝膠滲透層析儀(Gel Permeation Chromatography, GPC)、傅立葉轉換紅外線光譜儀(Fourier Transform Infrared Spectrometer, FTIR)、紫外光-可見光吸收光譜儀(UV-vis
spectrometer, UV-vis)和核磁共振光譜儀(Nuclear Magnetic Resonance Spectroscopy, NMR)鑑定所合成的多段嵌段高分子外，以高解析度穿透式電子顯微鏡(High Resolution Transmission Electron Microscopy, HRTEM)觀察自組裝行為。PNIPAM171-C60及C60-PNIPAM21-C60在常溫氯仿中自組裝為奈米環，加熱氯仿造成溶解度下降使PNIPAM171-C60形成較厚的奈米環而C60-PNIPAM21-C60形成奈米粒子，PNIPAM171-C60及C60-PNIPAM21-C60在水中主要自組裝為奈米粒子；PDMAEMA99-C60在常溫氯仿中形成網狀結構而C60-PDMAEMA67-C60形成奈米粒子，PDMAEMA99-C60和C60-PDMAEMA67-C60在水中自組裝為奈米粒子且粒子大小受到溫度影響。

Nanohybrids of stimuli-responsive polymers, including poly(N-isopropylacrylamide)、poly(2-(dimethylamino)ethyl methacrylate) and C60 have been prepared through sequential atom transfer radical polymerization. The samples have been characterized by gel permeation chromatography、FTIR、UV-vis and ¹H NMR. The self-assembly behaviors of the samples have been investigated by high resolution transmission electron microscopy. PNIPAM171-C60 and C60-PNIPAM21-C60 self-assemble into nano-toroids in chloroform at 25°C. PNIPAM171-C60 self-assembles into thick nano-toroids and C60-PNIPAM21-C60 self-assembles into nanoparticles in chloroform at elevated temperature due to the decrease in the solubility of the hybrids in chloroform. Both PNIPAM171-C60 and C60-PNIPAM21-C60 self-assemble into nanoparticles in water. PDMAEMA99-C60 self-assembles into network structures and C60-PDMAEMA67-C60 self-assembles into nanoparticles in chloroform at 25°C. PDMAEMA99-C60 and C60-PDMAEMA67-C60 self-assemble into nanoparticles in water. The size of nanoparticles is affected by temperature.

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