多重比較在微陣列技術上面的應用是很熱門的課題，為了能精準控制誤判率，通常採用的輔助方法是估計虛無假設的數目，再做進一步的計算。在這個領域上面，MD法有著不錯的表現，但是有些領域的研究需要更大量的基因，MD法的估計則會略顯保守，在這裡我們以改變程序起始點的方式對MD法做了一些修正，這個修正還可以選擇你可以接受的誤差的估計值。

Abstract
The Multiple test applied on microarray is still a hot issue. For precision estimation, a well-accepted method is to estimate the number of null hypotheses. In this topic MD method performs usefully. But the researcher may need more genes for his study. We build a adjusted method for this request. We change the starting location of the original method and plot a curve to choose the number depending on the standard deviation you can accept.

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