在此次的研究中，我們針對一共光程外差干涉之偏光儀進行改良。除了原有為了要減少量測中的外在因素對訊號所產生的干擾，而採用的共光程干涉技術，以及濾除非偵測頻率範圍的光源所造成的雜訊來提高系統的訊雜比，而採用的外差干涉技術之外，我們更換了一新型的相位可調式波片SBC及設計了一套樣品傳輸裝置去自動化我們的系統。我們以電腦控制SBC的相位延遲量與快軸角度，再以電磁閥搭配蠕動泵浦傳輸樣品，如此一來，可以穩定和精確地利用SBC去增強樣品對入射光源造成的旋光角度所引起的相位差訊號，而在衡量了訊雜比的相關性後，這個放大的能力約為45倍。在實驗中，利用改良後的共光程外差干涉式偏光儀去進行葡萄糖溶液的旋光角度及濃度量測，並且探討是否加入聚苯乙烯溶液造成散射性物質的情形。實驗結果顯示，在散射及非散射性物質的情形下，我們分別得到旋光角度解析能力為2.23×10-4、8.93×10-5度，其對應到濃度解析能力為5.6 mg/dl、2.2 mg/dl，而在偵測極限方面，同為15.6 mg/dl。我們預期若是系統的穩定性更加改善的話，此改良式的偏光儀在未來將非常有機會被應用於糖尿病患者的非侵入式血糖濃度偵測。

In this study, we improved an optical common-path heterodyne polarimeter. We not only utilize the common-path setup to reduce noises from the environment, but also use the heterodyne technique to pick up signals with other frequencies. Furthermore, we replace with the old phase-variable waveplate with a Soleil-Babinet compensater(SBC) and design a sample transmission setup to automate our system. We control the phase retardation and orientation angle of the SBC with specialized software installed in the computer. And collocate the electromagnetic valve and peristalsis pump to transmit sample solutions. Therefore, We can steadily and precisely enhance the phase difference signal induced by the chiral media. After the improvement, the system demonstrated an enhancement of about 45. We use this improved polarimeter to measure the optical rotation angles of different concentrations of glucose solution with and without polystyrene respectively. After calculating, the resolutions of optical rotation angle of glucose solution with and without polystyrene are 2.23×10-4 and 8.93×10-5 degree respectively, the corresponding concentration of glucose resolution are 5.6 mg/dl、2.2 mg/dl. For detection limit, both two cases have the same value 15.6 mg/dl. We expect that, by further improvement for stability, it can be applied in noninvasive blood glucose concentration monitoring for diabetics in the future.

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