本論文提出三種的光軸定心設計，也順利的找尋到目前較為合適的封裝液與透鏡液，並將兩者密度相等以忽略液體間浮力的影響，借此以輔助透鏡液的定型，讓液體透鏡之光軸定心得以達成，因此得以改善透鏡成像時，光軸偏移的像差問題。
本論文將探討液體透鏡光軸定心的兩個大主軸，一個為光軸的定位問題，另一個為透鏡液的定型問題；因此本文將敘述封裝液與透鏡所符合的條件特性，並且逐步的刪除較不可能的找尋方向，以較重要的液體互溶性之特性做為首要的尋找條件，成功的找尋到利用多元醇做為透鏡液與光學油做為封裝液的目前最合適之搭配，並將兩者密度相等以忽略液體間浮力的影響，便可成功的達成液體透鏡定型問題；另外則是利用液滴於固體表面的特性：如微結構表面、邊界效應，做為光軸定心設計的理論背景，將液體透鏡成功製作完成，並探討不同的定心設計所達到的光軸定心能力，量測的方法為光線通過液體透鏡後的beam profile所偏移之角度，本論文量測的結果發現，利用邊界效應的定心結構可以有效的把光軸的偏移角度，從無定心結構的接近0.9° 下降至0.1°以下。

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