虛實整合系統是工業4.0的關鍵應用之一，是一種結合電腦運算以及感測器和致動器裝置的整合系統。虛實整合系統實現人與網路的整合計算。導入虛實整合系統會提高產品的質量以及附加價值，而其複雜程度與使用性也會相對提高，虛實整合系統本身會受到它的複雜程度及使用性上的限制，因此本研究嘗試建立一套以機器學習為基礎的虛實整合系統，降低其複雜程度並提高使用性。本研究利用機器學習手法在虛實整合系統的虛擬子系統裡建立一套錯誤偵測與分類系統，此系統分為兩步驟，首先利用隨機森林演算法去分析從虛實整合系統感應器收集來的數據，來確定其關鍵變量，讓工程師可以知道是那些因素造成機台故障問題。第二步是建立長短期記憶神經網絡的時間序列學習模型，實現對機器的實時監控。在機器發生故障之前，錯誤偵測將發出警報並允許工程師調整機器參數或安排預測性維護以減輕機器停止運作的影響。在第一個案例研究裡，所提出的方法優於其他時間序列技術，並且能前3小時預測機台故障，其準確率達到80%或更高，並且在二個案例研究裡改善281%的產品壽命，此方法也可應用於其他的複雜系統，以提高機器利用率和生產力。

Cyber Physical System (CPS) is one of the key application of industry 4.0. CPS is an integrated system that combines computing, sensors and actuators. CPS is controlled by computer-based algorithms that integrate people and internet. However, the performance of CPS is limited by its computational complexity. How to implement CPS with less computational complexity and implement diagnostics, forecasting and equipment health management more efficiently in a real time performance remains an important issue. Therefore, the study attempts to establish an integrative machine learning method to reduce computational complexity and improve applicability as a virtual subsystem in CPS environment. This study consists of two steps. First, Random Forest (RF) is utilized to figure out key factors and reduce the data dimension for less computational complexity such that process engineers can figure out which factors are critical to the failure of machines. The second step is to establish a time series deep learning model based on Long Short-Term Memory (LSTM) network to achieve real time monitoring of machines. Before a machine fails, fault detection will alarm and allow the engineers to adjust parameters of machines or arrange predictive maintenance to mitigate the impact of machine shut-down. According to two empirical studies, the proposed method outperforms other times series techniques and the accuracy achieves 80 percent or higher 3 hours before machine down in a real time manner in the first case and improve the 281% productivity of a process in the second cases. This method can be applied to other complex systems to boost the efficiency of machine utilization and productivity.

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