本論文將報告作者於碩士班期間的研究成果.作者的工作分為兩類.第一部份是以x光結晶學的方法,決定金屬有機化合物的單晶結構.論文中將敘述下列八個單晶結構的配位幾何和各原子間的鍵長鍵角
晶體結構1 μ-oxalato-bis(tetramethylethylene diamine-isocyanato-copper(II)),

晶體結構2 bis(μ-dibromo)-bis(bromo-(1,4-diazacyclohepten)-copper(II)),

晶體結構3 tris(2-(2’-pyridine carboxaldimino) ethyl) amin)-cadmium(II)- thiocyanate-perchlorate

晶體結構4 bis((μ 2-azido-N,N)-azido-L-)cadmium(II) and bis((μ 2-azido-N,N)-nitrosyl-L-)cadmium(II)-hexafluorophosphate (L=N,N’-bis(alpha-(pyridin-2-yl) benzylidene) ethane-1,2-diamine)

晶體結構5 nitro-(2-phenylazo-pyridine)-(2,2’;6’2”-terpyridyl)-ruthenium(II)-tetrafluoroborate,

晶體結構6 dichloro-bis(1-ethyl-2(naphthyl-α-azo)imidazole)-osmium(II)

晶體結構7 cis-{(C-racemic-5,7,7,12,14,14-hexamethyl-1,4,8,11-tetraazacyclotetradecane) isothiocyanato)}nickel(II)

晶體結構8 chloro-(C-racemic-5,7,7,12,14,14-hexamethyl-1,4,8,11-tetraazacyclotetradecane)-nickle(II)

第二部份則是篩選下列三種蛋白質的養晶條件:

蛋白質1 Volvatoxin A2 (VAAII)

蛋白質2 Arginase

蛋白質3 Cardiotoxin 3 (CTXIII)

The thesis contains two branches of works during my master degree study. First, 8 crystal structures of metal organic complexes are determined by x-ray crystallography. Their coordination geometry about the metal center, bond lengths and bond angles are described in the thesis.
Crystal 1 μ-oxalato-bis(tetramethylethylene diamine-isocyanato-copper(II)),

Crystal 2 bis(μ-dibromo)-bis(bromo-(1,4-diazacyclohepten)-copper(II)),

Crystal 3 tris(2-(2’-pyridine carboxaldimino) ethyl) amin)-cadmium(II)- thiocyanate-perchlorate

Crystal 4 bis((μ 2-azido-N,N)-azido-L-)cadmium(II) and bis((μ 2-azido-N,N)-nitrosyl-L-)cadmium(II)-hexafluorophosphate (L=N,N’-bis(alpha-(pyridin-2-yl) benzylidene) ethane-1,2-diamine)

Crystal 5 nitro-(2-phenylazo-pyridine)-(2,2’;6’2”-terpyridyl)-ruthenium(II)-tetrafluoroborate,

Crystal 6 dichloro-bis(1-ethyl-2(naphthyl-α-azo)imidazole)-osmium(II)

Crystal 7 cis-{(C-racemic-5,7,7,12,14,14-hexamethyl-1,4,8,11-tetraazacyclotetradecane) isothiocyanato)}nickel(II)

Crystal 8 chloro-(C-racemic-5,7,7,12,14,14-hexamethyl-1,4,8,11-tetraazacyclotetradecane)-nickle(II)

Second, the screening of crystallization conditions for three purified proteins:

Protein 1 Volvatoxin A2 (VAAII)

Protein 2 Arginase

Protein 3 Cardiotoxin 3 (CTXIII)

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