本研究選擇聚己內酯（Poly(ε-caprolactone), PCL）、聚麩胺酸（γ-Polyglutamic acid, γ-PGA）和硫酸軟骨素（Chondroitin sulfate, CS）做成複合支架。先合成γ-PGA接枝CS的共聚物，然後利用IR和NMR進行合成結構鑑定。之後利用微粒溶濾法製作不同比例的三維多孔性支架，讓PCL重量比例較高，維持支架的機械強度。最後植入軟骨細胞進行細胞培養，比較不同支架中細胞的生長情形。研究中測量得知共聚物含量佔支架30wt%時含水率約有740%，高於其他含量較低的支架。經過軟骨細胞培養的支架進行切片染色、GAGs assay及collagen assay後，實驗結果也顯示出共聚物含量30wt%的支架細胞生長情形優於其他的支架。各個實驗數據都顯示出共聚物的添加對細胞生長和細胞外間質的分泌造成一定程度的助益。

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