中文摘要
本論文由胺基酸及水楊醛合成一系列掌性釩錯合物，並試著將掌性錯合物應用於不對稱腈醇的合成。
利用釩錯合物17為催化劑以丙酮為溶劑則可催化生成腈醇產物。在此催化系統最佳的反應溶劑為丙酮，而非一般腈醇反應常用的二氯甲烷或四氫呋喃。在芳香醛的例子，鏡像選擇性介於59~87%，而脂肪醛的鏡像選擇性較差一些，17之化學結構最好可達83%。

Abstract
A series of chiral vanadium complexes were prepared with amino acid and salicylaldehyde. These chiral complexes have been utilized in the studies of asymmetric coupling of 2-naphthols, chiral cyanohydrins and chiral aminonitriles syntheses.
For the cyanohydrins synthesis, the complex 17 was able to catalyze trimethylsilyl cyanaion of aldehyde in acetone. The best reaction solvent was acetone in this catalytic system rather than dichrolomethane or THF. The chiral cyanohydrins were obtained in high yield with 72-90% ee.

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